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Updated: Jun 6, 2025
Author Spotlight: Optimizing Scorpion Venom Extraction for Antivenom Production
Published on: October 6, 2023
Scorpion serotherapy during pregnancy protects rat offspring from harmful effects of venom
Guilherme Gonelli Paz1, Maria Eliza Ferreira do Val de Paulo2, Ana Leonor Abrahão Nencioni2
1Post-Graduation Program in Science - Toxinology of Butantan Institute, Av. Dr. Vital Brazil 1500, São Paulo, 05503-900, Brazil; Laboratory of Biochemistry and Biophysics, Butantan Institute, Av. Dr. Vital Brazil 1500, São Paulo, 05503-900, Brazil.
Abstract:
Despite the numerous incidents of scorpion envenoming worldwide, little is known about the effects of maternal venom exposure and serotherapy on fetal development. The impact of antivenom on pregnant rats envenomed by Tityus serrulatus venom was examined. The venom caused alterations in the development of the offspring, yet the antivenom protected against these adverse effects and does not cause harm in itself, indicating the potential benefits of serotherapy.
