Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

157
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
157
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

51
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
51
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

57
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
57
Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

316
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
316
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

121
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
121
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

66
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
66

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Complications Rates After Total Knee Arthroplasty in Patients With Peripheral Vascular Disease.

The journal of knee surgery·2026
Same author

Induced Membrane Wrist Fusion with Ring External Fixator Assistance in a Mangled Upper Extremity: A Case Report.

Journal of orthopaedic case reports·2025
Same author

Effect of Lumbar Erector Spinae Plane Blocks After Lumbar Fusion Surgery: A Randomized Control Trial.

Clinical spine surgery·2025
Same author

Evaluation of Adult Reconstruction and Arthroplasty Fellowships in the United States Based on Academic Productivity.

Arthroplasty today·2024
Same author

Defining and Understanding Diagnostic Delays Among Pancreatic Cancer Patients: A Retrospective Cohort Study.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2024
Same author

Roussouly classification of adult spinal deformity.

Proceedings (Baylor University. Medical Center)·2024

Related Experiment Video

Updated: Jun 6, 2025

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

6.9K

Interval Advanced Adenomas and Neoplasia in Patients with Negative Colonoscopy Following Positive Stool-Based

Kyle S Liu1, Rollin George2, Caleb Shin3

  • 1Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO, USA.

Digestive Diseases and Sciences
|November 24, 2024
PubMed
Summary

Following a positive fecal occult blood test (FOBT) or fecal immunohistochemical test (FIT) for colorectal cancer screening, a negative colonoscopy indicates a low risk of advanced adenomas. Non-Hispanic white individuals with negative colonoscopies may benefit from closer surveillance.

Keywords:
Colon polypsColonoscopyFecal immunohistochemical testFecal occult blood testSurveillance

More Related Videos

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

31.7K
Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
28:15

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Published on: July 28, 2010

12.3K

Related Experiment Videos

Last Updated: Jun 6, 2025

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

6.9K
Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

31.7K
Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
28:15

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Published on: July 28, 2010

12.3K

Area of Science:

  • Gastroenterology
  • Oncology
  • Preventive Medicine

Background:

  • Fecal occult blood tests (FOBT) and fecal immunohistochemical tests (FIT) are crucial for colorectal cancer (CRC) screening.
  • The risk of developing advanced adenomas or CRC after a positive FOBT/FIT followed by a negative colonoscopy remains unclear.

Purpose of the Study:

  • To determine the incidence of advanced adenomas or CRC after a negative colonoscopy in patients with a positive FOBT/FIT.
  • To identify risk factors for developing advanced adenomas or CRC in this patient group.

Main Methods:

  • A retrospective cohort study identified patients who underwent colonoscopy after a positive FOBT/FIT between 2010 and 2013.
  • Incidence rates of advanced adenomas or CRC were compared between patients with negative and positive index colonoscopies.
  • Cox regression models were used to examine risk factors for incident adenomas.

Main Results:

  • Of 2096 patients, 1293 (61.7%) had negative index colonoscopies.
  • The incidence rate of advanced adenomas was significantly higher after positive colonoscopies (2.08 per 100 person-years) compared to negative colonoscopies (0.65 per 100 person-years).
  • Non-Hispanic white race was identified as the strongest risk factor for incident adenomas in patients with negative index colonoscopies.

Conclusions:

  • A negative colonoscopy following a positive FOBT/FIT is associated with a low likelihood of developing advanced adenomas and no interval CRC.
  • Non-Hispanic white race is a risk factor for incident adenomas, suggesting these patients may require more intensive surveillance.