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Home-based, computer-assisted cognitive rehabilitation for attention in pediatric onset multiple sclerosis: a
Camilla Masciulli1, E Portaccio2, B Goretti2
1Department of NEUROFARBA, University of Florence, Largo Piero Palagi, 1, Florence, 50139, Italy. camilla.masciulli@unifi.it.
Summary
This study explored computer-assisted attention training for pediatric Multiple Sclerosis (MS) patients. Specific training showed promising improvements in cognitive function, suggesting a potential benefit for attention in pediatric MS.
Area of Science:
- Neurology
- Neurorehabilitation
- Pediatric Medicine
Background:
- Cognitive impairment is prevalent in pediatric onset Multiple Sclerosis (POMS), impacting daily life.
- Effective interventions for cognitive deficits in POMS are needed.
Purpose of the Study:
- To assess the feasibility and effectiveness of a home-based, computer-assisted attention training program for POMS patients.
- To evaluate the impact of specific training (ST) versus non-specific training (n-ST) on attention.
Main Methods:
- A randomized double-blind study design was employed.
- Participants received either specific training (ST) or non-specific training (n-ST) via the COGNI-TRAcK2 module.
- The Symbol Digit Modalities Test (SDMT) was the primary outcome measure, with assessments at baseline, post-training, and 3-month follow-up.
Main Results:
- The specific training (ST) group demonstrated a significant improvement in SDMT scores from baseline to 3-month follow-up (p=0.043).
- No significant benefits were observed in other neuropsychological measures for the ST group.
- Limited patient data (5 in ST, 8 in n-ST) were available for analysis.
Conclusions:
- Preliminary results suggest that home-based, computer-assisted attention training may benefit patients with POMS.
- Further research with larger sample sizes is warranted to confirm these findings.
