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A Road Map to Hepatitis C Elimination: Yesterday, Today, and Tomorrow

Luis A Gonzalez Corro1, Gregory M Lucas2, Kathleen R Page2

  • 1Division of Infectious Diseases, New York University School of Medicine, New York, New York, USA.

Open Forum Infectious Diseases
|November 25, 2024
PubMed

Insights

Hepatitis C virus (HCV) infection impacts millions in the US, with rising cases and deaths. Eradicating HCV requires addressing social determinants of health alongside biomedical tools.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Health Policy

Background:

  • An estimated 3.5 million individuals in the US have hepatitis C virus (HCV) infection.
  • HCV-related deaths reached 15,000 in 2019, with annual healthcare costs around $7 billion.
  • Despite previous declines, hepatitis C infections have resurged in the US since 2010.

Purpose of the Study:

  • To highlight the ongoing public health challenge posed by hepatitis C virus (HCV) infection in the United States.
  • To emphasize the critical role of social determinants of health in achieving better patient outcomes.
  • To advocate for cohesive action among public health systems, hospital networks, and governments to eradicate HCV.

Main Methods:

  • This study is a review and analysis of the current state of hepatitis C virus (HCV) infection in the US.
  • It synthesizes information on HCV incidence, mortality, costs, and treatment advancements.
  • It examines the impact of social determinants of health on HCV outcomes and proposes a public health strategy.

Main Results:

  • Hepatitis C virus (HCV) infection remains a significant public health issue in the US, characterized by increasing incidence and substantial mortality.
  • Current biomedical treatments, while successful, are insufficient alone to curb the epidemic.
  • Social determinants of health profoundly influence health outcomes for individuals with HCV, necessitating integrated interventions.

Conclusions:

  • The eradication of hepatitis C virus (HCV) is achievable through a combination of advanced biomedical treatments and targeted social interventions.
  • A coordinated effort involving public health systems, healthcare providers, and governmental bodies is essential.
  • Addressing social determinants of health is paramount to overcoming the hepatitis C epidemic and improving patient outcomes.

Keywords:
health disparitieshealth equityhepatitis Csocial determinants of healthsubstance use

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