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Primary pancreatic lymphoma: A case report and review of literature
Marko M Stojanovic1, Vesna Brzacki1, Goran Marjanovic2
1Department of Gastroenterology and Hepatology Clinic, University Clinical Center Nis, Medical Faculty University of Nis, Nis 18000, Serbia.
Background:
Primary pancreatic lymphoma (PPL) is a rare tumor that mimics pancreatic adenocarcinoma, leading to diagnostic and therapeutic challenges. PPL accounts for 0.2% of all pancreatic tumors and is typically treated with chemotherapy. However, the long-term survival rates for PPL with chemotherapy and radiotherapy alone are unsatisfactory. Due to the improvements in pancreatic surgery, there is a need to reevaluate the treatment strategies for PPL.
Case Summary:
A 62-year-old male presented to our clinic. A biopsy was unsuccessful, and the imaging was suggestive of pancreatic adenocarcinoma. Therefore, subtotal splenopancreatectomy was performed and histopathology was performed. He was then diagnosed with primary pancreatic diffuse large B-cell lymphoma. He received adjuvant chemotherapy and radiotherapy. Currently, the patient is alive with no evidence of disease 36 months after surgery.
Conclusion:
The potential role of surgery in the treatment of PPL should be emphasized and added in the management protocol of early stage lymphoma.
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