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Role of immunotherapy in gastric cancer with liver metastasis

Bogdan Gafton1,2, Stefan Morarasu3, Gabriel Dimofte4

  • 1Department of Oncology, Regional Institute of Oncology, Iasi 700483, Romania.

World Journal of Clinical Oncology
|November 25, 2024
PubMed

Insights

Gastric cancer remains a public health concern with high mortality. New biologic treatments and immunotherapy offer expanded options for metastatic gastric cancer, improving quality of life and survival.

Area of Science:

  • Oncology
  • Gastroenterology
  • Public Health

Background:

  • Gastric cancer presents a significant public health challenge due to high mortality rates, despite a declining incidence.
  • Liver metastasis is the most common site of spread for gastric cancer, followed by the peritoneum, lungs, and bones.

Discussion:

  • The therapeutic landscape for metastatic gastric cancer has evolved with the integration of biologic treatments and immunotherapy.
  • These advancements aim to improve patient outcomes, focusing on enhanced quality of life and prolonged survival.

Key Insights:

  • Metastatic gastric cancer, particularly with liver involvement, benefits from novel therapeutic strategies.
  • Biologic therapies and immunotherapy represent significant progress in managing advanced gastric cancer.

Outlook:

  • Continued research into targeted therapies and immunotherapies holds promise for further improving survival and quality of life in patients with metastatic gastric cancer.
  • Personalized treatment approaches may optimize outcomes for individuals with gastric cancer and liver metastases.
Keywords:
Gastric cancerImmunotherapyLiver metastasesMetastatic gastric cancerOncologySurgical oncology

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