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Ethnomedicinal breakthroughs in snake bite therapy: From folklore to forefront
Sana S Hussain1, Danie Kingsley1
1Department of Integrative Biology, School of BioSciences and Technology, VIT, Vellore, India.
Toxicology Reports
|November 25, 2024
Summary
Ethnomedicinal herbs show promise as affordable adjuncts to antivenoms for snakebite envenomation, particularly in regions like India. Further research, including bioinformatics, is needed to optimize their use alongside traditional treatments.
Area of Science:
- Medical Science
- Pharmacology
- Ethnobotany
Background:
- Snakebite envenomation is a major public health concern in tropical regions, causing significant mortality and morbidity.
- Conventional antivenoms face challenges including high cost, limited accessibility, and adverse side effects.
- Regional and species-specific variations in snake venom complicate the development of effective antivenoms.
Purpose of the Study:
- To review the potential of ethnomedicinal herbs as complementary therapies for snakebite envenomation.
- To explore the challenges associated with conventional antivenom treatments.
- To investigate the role of bioinformatics in enhancing snakebite treatment research.
Main Methods:
- Literature review of ethnomedicinal practices for snakebite treatment.
- Analysis of pharmacological properties of medicinal plants against snake venom.
- Exploration of bioinformatics tools for antivenom development.
Main Results:
- Certain medicinal plants demonstrate pharmacological potential in neutralizing snake venom effects.
- Ethnomedicinal herbs offer a more accessible and affordable alternative or adjunct to antivenoms.
- Variability in efficacy exists due to regional snake venom differences.
Conclusions:
- Ethnomedicinal herbs represent a promising avenue for developing adjunct therapies for snakebite envenomation.
- Integrating traditional knowledge with modern scientific approaches, including bioinformatics, can lead to improved snakebite treatments.
- Further research is crucial to validate efficacy and standardize the use of these herbal therapies in resource-limited settings.
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