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Updated: Jun 6, 2025

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Data-driven models for microfluidics: A short review
Yu Chang1, Qichen Shang1, Zifei Yan1
1Department of Chemical Engineering, State Key Laboratory of Chemical Engineering, Tsinghua University, Beijing 100084, China.
Abstract:
Microfluidic devices have many unique practical applications across a wide range of fields, making it important to develop accurate models of these devices, and many different models have been developed. Existing modeling methods mainly include mechanism derivation and semi-empirical correlations, but both are not universally applicable. In order to achieve a more accurate and general modeling process, the use of data-driven modeling has been studied recently. This review highlights recent advances in the application of data-driven modeling techniques for simulating and designing microfluidic devices. First, it introduces the application of traditional modeling approaches in microfluidics; subsequently, through different database sources, it reviews studies on data-driven modeling in three categories; and finally, it raises some open issues that require further investigation.
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