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Castleman disease mimicking accessory spleen on imaging: A case report
Niloofar Ayoobi Yazdi1, Arman MomeniAmjadi1, Rad Ghannadzadeh Kermanipour2
1Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Tehran University of Medical Sciences, Tehran, Iran.
Radiology Case Reports
|November 25, 2024
Summary
Castleman disease (CD), a rare lymphoproliferative disorder, presents diagnostic challenges. This case highlights retroperitoneal Unicentric Castleman
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Castleman disease (CD) is a rare, non-neoplastic lymphoproliferative disorder.
- Unicentric Castleman's Disease (UCD) typically presents as localized lymph node enlargement.
- CD often mimics other benign and malignant conditions, complicating diagnosis.
Observation:
- A 19-year-old male presented with nonspecific left upper quadrant pain.
- Imaging revealed a hypervascular retroperitoneal mass, initially suspected as an accessory spleen or neuroendocrine tumor.
- Surgical resection and histopathology confirmed hyaline-vascular type UCD.
Findings:
- Retroperitoneal UCD presents unique diagnostic challenges due to its uncommon location.
- Imaging modalities frequently fail to definitively distinguish UCD from other vascular lesions.
- Histopathological analysis remains crucial for accurate UCD diagnosis.
Implications:
- Increased awareness of UCD in unusual locations is necessary for timely diagnosis.
- Advanced imaging and histopathology are vital for accurate diagnosis and effective treatment.
- A multidisciplinary approach ensures optimal management and favorable patient outcomes for UCD.
