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Updated: Jun 6, 2025

Experimental Metastasis Assay
Published on: August 24, 2010
Unmasking the Origin of Cutaneous Metastasis: A Case Report
Paola Campillo1, Adriana Morales Rivera1, Alice Kesler1
1Internal Medicine, Lakeland Regional Health, Lakeland, USA.
Abstract:
Cutaneous metastasis typically represents a late manifestation of internal malignancy. We present the case of a 60-year-old woman with a history of cervical cancer who presented with lower abdominal pain. Imaging studies revealed a high-grade carcinoma involving the urothelium, suggestive of primary urothelial carcinoma. Further investigation uncovered widespread metastatic disease, including cutaneous metastases to the arm and pelvis. Despite a comprehensive diagnostic workup, including immunohistochemical analysis, the primary tumor site could not be definitively identified, underscoring the challenges in diagnosing cutaneous metastases of unknown origin. This case highlights the necessity of considering metastatic disease in patients with atypical skin findings. Moreover, it emphasizes the aggressive nature of cutaneous metastases, particularly those originating from urothelial carcinomas, which are associated with a poor prognosis and limited treatment options.
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