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Updated: Jun 6, 2025
Quantitative Micro-CT Analysis of Aortopathy in a Mouse Model of β-aminopropionitrile-induced Aortic Aneurysm and Dissection
Published on: July 16, 2018
Advancements in Cardiovascular Imaging: Substituting Magnetic Resonance Imaging for Contrast-Enhanced Computed
Toru Miyoshi1, Fuminori Shinozuka2, Toshio Honda3
1Department of Cardiology, Pulmonology, Hypertension, and Nephrology, Graduate School of Medicine, Ehime University, Toon City, JPN.
Abstract:
A male in his seventies was admitted for a patent ductus arteriosus (PDA) closure. We planned a catheter-based closure but avoided pre-procedural contrast-enhanced CT due to his low estimated glomerular filtration rate. Instead, we used magnetic resonance imaging (MRI) (Philips, 3T, Ingenia Elition, Philips Healthcare, Amsterdam, The Netherlands). An MRI of the aorta showed that the PDA was aneurysmal (Krichenko classification, type D). The Qs/Qp ratio via two-dimensional phase-contrast MRI was 1.78. Black blood imaging was used to obtain accurate diameter determination. Black Blood Imaging and aortography did not differ in any dimension. The procedure was completed using an Amplatzer Vascular Plug II (Abbott, Abbott Park, IL) 16 × 12 mm, achieving PDA closure without complications, and the patient was discharged. MRI provided an accurate assessment of the vascular morphology using non-contrast-enhanced black blood imaging, suggesting a gradual change in PDA morphology.
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