Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis II: Clinical features and Diagnostic Tests01:25

Endocarditis II: Clinical features and Diagnostic Tests

2
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
2
Skin Cancer01:30

Skin Cancer

3.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
3.7K
Myocarditis II: Clinical features and Diagnostic Tests01:27

Myocarditis II: Clinical features and Diagnostic Tests

2
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
2
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

7
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
7
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

3
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
3
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rapid efficacy of anifrolumab in refractory cutaneous dermatomyositis.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Psychiatric Outcomes after GLP-1 Receptor Agonists versus Metformin in Hidradenitis Suppurativa.

Skin appendage disorders·2026
Same author

Patterns of excess and cause-specific mortality in vulvar squamous cell carcinoma: a Surveillance, Epidemiology, and End Results program population-based study.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2026
Same author

Therapeutic Infliximab Levels Are Associated With Improved Clinical Outcomes in Hidradenitis Suppurativa: A Pilot Retrospective Cohort Study.

Journal of the American Academy of Dermatology·2026
Same author

Isolated perianal hypertrophic lichen planus in men.

Clinical and experimental dermatology·2026
Same author

Drug-related pseudolymphoma: Insights from the Food and Drug Administration Adverse Event Reporting System.

Journal of the American Academy of Dermatology·2026

Related Experiment Video

Updated: Jun 6, 2025

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response
06:31

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response

Published on: October 3, 2019

8.6K

Erythema multiforme.

Elio Kechichian1, Nicolas Dupin2,3, David A Wetter4

  • 1Department of Dermatology, University of Sherbrooke, Sherbrooke, Quebec, Canada.

Eclinicalmedicine
|November 25, 2024
PubMed
Summary

Erythema multiforme is an inflammatory skin condition often triggered by infections. Prompt diagnosis and management, including ruling out Mycoplasma pneumoniae, are key for patient recovery and preventing complications.

Keywords:
Erythema multiformeHerpes simplex virusMycoplasma pneumoniae

More Related Videos

Minimal Erythema Dose MED Testing
06:24

Minimal Erythema Dose MED Testing

Published on: May 28, 2013

41.6K
Multifocal Electroretinograms
16:49

Multifocal Electroretinograms

Published on: December 4, 2011

18.2K

Related Experiment Videos

Last Updated: Jun 6, 2025

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response
06:31

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response

Published on: October 3, 2019

8.6K
Minimal Erythema Dose MED Testing
06:24

Minimal Erythema Dose MED Testing

Published on: May 28, 2013

41.6K
Multifocal Electroretinograms
16:49

Multifocal Electroretinograms

Published on: December 4, 2011

18.2K

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Immunology

Background:

  • Erythema multiforme (EM) is an inflammatory skin and mucosal condition.
  • It is primarily linked to infectious agents like Herpes simplex virus and Mycoplasma pneumoniae, but can be idiopathic.
  • EM presents with characteristic target lesions on the skin and can affect oral mucosa, causing severe pain and impacting nutrition.

Purpose of the Study:

  • To provide a comprehensive understanding of Erythema multiforme's clinical features, triggers, and differential diagnoses.
  • To outline essential workup and management strategies for EM.
  • To discuss the challenges and emerging treatments for persistent or recurrent EM.

Main Methods:

  • Review of clinical characteristics of Erythema multiforme.
  • Analysis of triggering agents, including infectious causes.
  • Discussion of differential diagnosis, focusing on Stevens-Johnson syndrome/Toxic Epidermal Necrolysis.
  • Evaluation of management strategies, encompassing symptomatic, etiologic, and advanced treatments for refractory cases.

Main Results:

  • Erythema multiforme diagnosis requires understanding its varied clinical presentations and triggers.
  • Mycoplasma pneumoniae infection necessitates immediate identification due to antibiotic treatment requirements.
  • Symptomatic and etiologic treatments form the basis of EM management.
  • Recurrent or persistent EM cases may require advanced therapeutic interventions when standard treatments fail.

Conclusions:

  • Accurate diagnosis and prompt management of Erythema multiforme are crucial, especially ruling out Mycoplasma pneumoniae.
  • Effective management involves symptomatic care, etiological treatment, and tailored approaches for persistent or recurrent cases.
  • Understanding differential diagnoses like Stevens-Johnson syndrome is vital for appropriate patient care.