Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Data Resource Profile: The China National Health Survey (CNHS).

International journal of epidemiology·2018
Same author

New Pathway for Hot Electron Relaxation in Two-Dimensional Heterostructures.

Nano letters·2018
Same author

A Dual-Band Multilayer InSe Self-Powered Photodetector with High Performance Induced by Surface Plasmon Resonance and Asymmetric Schottky Junction.

ACS nano·2018
Same author

Two-minute walk test: Reference equations for healthy adults in China.

PloS one·2018
Same author

The Dysregulation of the <i>DLK1</i>-<i>MEG3</i> Locus in Islets From Patients With Type 2 Diabetes Is Mimicked by Targeted Epimutation of Its Promoter With TALE-DNMT Constructs.

Diabetes·2018
Same author

Co-regulatory networks of human serum proteins link genetics to disease.

Science (New York, N.Y.)·2018

Related Experiment Video

Updated: Jun 6, 2025

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.3K

[Research progress in stimuli-responsive microneedles for biomedical applications].

Jia Zhang1,2,3, Yang Su1,2,3, Tongtong Zhao1,2,3

  • 1Bloomage Biotechnology (Hainan) Co., Ltd., Haikou 570300, Hainan, China.

Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|November 25, 2024
PubMed
Summary

Stimuli-responsive microneedles offer a minimally invasive transdermal drug delivery system. This advanced method enhances drug penetration and therapeutic effects by responding to specific stimuli, overcoming traditional administration challenges.

Keywords:
biosensingdrug deliverymicroneedlingrelease mechanismresponse to stimuli

More Related Videos

Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability
07:41

Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability

Published on: July 12, 2024

2.0K
Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

12.0K

Related Experiment Videos

Last Updated: Jun 6, 2025

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.3K
Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability
07:41

Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability

Published on: July 12, 2024

2.0K
Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

12.0K

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Pharmacology

Background:

  • Conventional drug delivery faces challenges like low bioavailability and patient discomfort.
  • Transdermal drug delivery is hindered by the skin's stratum corneum barrier.
  • Microneedling offers a minimally invasive approach for enhanced local drug delivery.

Purpose of the Study:

  • To review stimuli-responsive microneedles for drug delivery.
  • To discuss materials, types, and release mechanisms of these microneedles.
  • To explore biomedical applications and future challenges of stimuli-responsive microneedles.

Main Methods:

  • Literature review of stimuli-responsive microneedle technology.
  • Analysis of materials, fabrication, and drug release mechanisms.
  • Examination of biomedical applications across various stimuli-responsive systems.

Main Results:

  • Stimuli-responsive microneedles provide spatiotemporal control and high drug delivery efficiency.
  • Various materials and designs enable tailored drug release in response to stimuli.
  • Demonstrated efficacy in biomedical applications with potential for reduced side effects.

Conclusions:

  • Stimuli-responsive microneedles represent a promising advancement in transdermal drug delivery.
  • Further research is needed to address challenges and optimize clinical translation.
  • This technology holds potential for improved therapeutic outcomes and patient compliance.