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The importance of cognitive correlates of plasma amyloid-β 42/40
Andrea M Weinstein1,2, Marissa A Gogniat3, Meryl A Butters1,2
1School of Medicine, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Abstract:
This commentary focuses on the clinical utility of plasma amyloid-β (Aβ) 42/40 to detect semantic intrusion errors in amnestic mild cognitive impairment, as investigated Curiel Cid et al. in a recent issue of the Journal of Alzheimer's Disease. This commentary highlights the importance of testing the sensitivity of plasma Aβ42/40 to clinical symptoms in the quest to develop a comprehensive definition of AD that incorporates both biological precursors and clinical consequences.
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