A Simple Clinical Predictive Model for Arthroscopic Mobility of Osteochondritis Dissecans Lesions of the Knee
- Matthew D Milewski 1,2, Patricia E Miller 1,2, Emma C Gossman 1,2, Ryan P Coene 1,2, Marc A Tompkins 3,2, Christian N Anderson 4,2, Kathryn Bauer 5,2, Michael T Busch 6,2, James L Carey 7,2, Sasha Carsen 8,2, Henry G Chambers 9,2, Ryan P Coene 1,2, Eric W Edmonds 10,2, Jutta Ellermann 11,2, Henry B Ellis 12,2, John Erickson 13,2, Peter D Fabricant 14,2, Theodore J Ganley 15,2, Emma C Gossman 1,2, Daniel W Green 14,2, Benton E Heyworth 16,2, James Hoi Po Hui 17,2, Mininder S Kocher 16,2, Aaron J Krych 18,2, Kevin Latz 19,2, Roger M Lyon 20,2, Stephanie Mayer 21,2, Matthew D Milewski 22,2, Patricia E Miller 1,2, Bradley J Nelson 11,2, Jeffrey J Nepple 23,2, Jie C Nguyen 24,2, Carl W Nissen 25,2, James Lee Pace 5,2, Mark V Paterno 26,2, Andrew T Pennock 27,2, Crystal Perkins 6,2, John D Polousky 28,2, Paul Saluan 29,2, Kevin G Shea 30,2, Marc A Tompkins 31,2, Eric J Wall 32,2, Jennifer M Weiss 33,2, Clifton Willimon 6,2, Philip Wilson 12,2, Rick W Wright 34,2, Andy Zbojniewicz 35,2, Gregory D Myer 36,2
- Matthew D Milewski 1,2, Patricia E Miller 1,2, Emma C Gossman 1,2
- 1Division of Sports Medicine, Department of Orthopaedic Surgery, Boston Children's Hospital, Boston, Massachusetts.
- 2Investigation performed at the Division of Sports Medicine, Department of Orthopaedic Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.
- 3Gillette Children's Specialty Healthcare, Minneapolis, Minnesota; University of Minnesota, Minneapolis, Minnesota; TRIA Orthopaedic Center, Minneapolis, Minnesota.
- 4Tennessee Orthopaedic Alliance, Nashville, Tennessee.
- 5Children's Health Andrews Institute, Plano, Texas.
- 6Children's Healthcare of Atlanta, Atlanta, Georgia.
- 7University of Pennsylvania, Philadelphia, Pennsylvania.
- 8University of Ottawa, Ottawa, Canada.
- 9San Diego Children's Hospital, San Diego, California.
- 10Rady Children's Hospital San Diego, San Diego, California.
- 11University of Minnesota, Minneapolis, Minnesota.
- 12Texas Scottish Rite Hospital for Children, Dallas, Texas.
- 13Children's Wisconsin, Milwaukee, Wisconsin.
- 14Hospital for Special Surgery, New York, New York.
- 15The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
- 16Boston Children's Hospital, Boston, Massachusetts.
- 17National University of Singapore, Singapore.
- 18Mayo Clinic, Rochester, Minnesota.
- 19Children's Mercy Hospital, Kansas City, Missouri.
- 20Medical College of Wisconsin, Milwaukee, Wisconsin.
- 21University of Colorado, Englewood, Colorado.
- 22Division of Sports Medicine, Department of Orthopaedic Surgery, Boston Children's Hospital, Boston, Massachusetts, and Harvard Medical School, Boston, Massachusetts.
- 23Washington University School of Medicine in St Louis, St Louis, Missouri.
- 24Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
- 25University of Connecticut, Farmington, Connecticut.
- 26Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
- 27Rady Children's Hospital, San Diego, California.
- 28Akron Children's Hospital, Akron, Ohio.
- 29Cleveland Clinic, Cleveland, Ohio.
- 30Stanford School of Medicine, Stanford, California.
- 31Gillette Children's Specialty Healthcare, University of Minnesota, and TRIA Orthopaedic Center, Minneapolis, Minnesota.
- 32Cincinnati Children's Hospital, Cincinnati, Ohio.
- 33Shriners Children's Hawai'i, Honolulu, Hawai'i.
- 34Vanderbilt University Medical Center, Nashville, Tennessee.
- 35Grand Rapids, Michigan.
- 36Emory Sports Performance and Research Center(SPARC), Flowery Branch, Georgia; Emory Sports Medicine Center, Atlanta, Georgia; Emory Sports Medicine Center, Atlanta, Georgia, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, Georgia.
- 0Division of Sports Medicine, Department of Orthopaedic Surgery, Boston Children's Hospital, Boston, Massachusetts.
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View abstract on PubMed
Summary
This summary is machine-generated.Age, knee effusion, and reduced range of motion can predict osteochondritis dissecans (OCD) lesion mobility before surgery. This aids in planning treatment and counseling patients and families.
Area Of Science
- Orthopedics
- Pediatric Orthopedics
- Sports Medicine
Background
- Osteochondritis dissecans (OCD) of the knee involves subchondral bone and cartilage, posing risks for instability and osteoarthritis.
- Treatment decisions for knee OCD depend on patient and lesion factors, notably lesion mobility.
Purpose Of The Study
- To develop a multivariable model predicting knee OCD lesion mobility pre-arthroscopically.
- Incorporate patient demographics and physical examination findings into the predictive model.
Main Methods
- A prospective, multicenter cohort study included patients under 19 with arthroscopically confirmed OCD mobility.
- Multivariable logistic regression analyzed factors predicting mobile vs. immobile lesions, with data split for training and validation.
- Model performance assessed using sensitivity, specificity, and AUC on holdout data.
Main Results
- The final predictive model included age ≥14 years, knee effusion, and loss of range of motion.
- Controlling variables were male sex and weight >54.4 kg.
- The model achieved 83% sensitivity, 82% specificity, and an AUC of 0.89 in the validation cohort.
Conclusions
- Chronologic age, presence of effusion, and loss of motion are significant predictors of knee OCD lesion mobility.
- This predictive capability can enhance surgical planning and patient/family counseling regarding treatment options.
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