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Updated: Jun 6, 2025
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Prognostic Scores for Acute Kidney Injury in Critically Ill Patients
Wisble Pereira Sousa1, Marcia Cristina da Silva Magro1, Alberto Augusto Martins Paiva2
1Faculty of Health Sciences and Technology, University of Brasília/UnB, Brasília 72220-275, Brazil.
Background:
Numerous prognostic scores have been developed and used in intensive care; however, the applicability and effectiveness of these scores in critically ill patients with acute kidney injury may vary due to the characteristics of this population.
Objective:
To assess the predictive capacity of the Simplified Acute Physiology Score III (SAPS III), Sequential Sepsis-related Organ Failure Assessment (SOFA) and Nursing Activities Score (NAS) prognostic scoring systems for acute kidney injury in critically ill patients.
Methods:
Cohort, prospective and quantitative study with follow-up of 141 critical patients in intensive care. A questionnaire was used to collect information about the capacity of prognostic scoring systems to predict AKI. Mann-Whitney, Kruskal-Wallis and Bonferroni-corrected Mann-Whitney tests were used and the statistical significance was considered to be at two-sided p < 0.05.
Results:
It was revealed that 41.85% of patients developed acute kidney injury during their stay in the Intensive Care Unit and indicated greater severity assessed by the medians of prognostic scoring systems-SAPS III [55 (42-65 vs. 38 (32-52), p < 0.001], SOFA [3.3 (2.26-5.00) vs. 0.66 (0.06-2.29), p < 0.001] and NAS [90 (75-95) vs. 97 (91-103), p < 0.001]-when compared to patients without kidney damage.
Conclusions:
The SAPS III, SOFA and NAS prognostic scoring systems showed good predictive capacity for acute kidney injury in critically ill patients. This study was not registered.
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