Targeted Temperature Management After Pediatric Cardiac Arrest: A Quality Improvement Program With Multidisciplinary

Mason P McMullin1,2, Noelle B Cadotte3, Erin M Fuchs4

  • 1Department of Pediatrics, Uniformed Services University, Bethesda, MD.

Insights

Implementing a targeted temperature management (TTM) bundle significantly reduced fever duration in pediatric cardiac arrest survivors. This quality improvement initiative improved patient outcomes by minimizing fever time post-cardiac arrest.

Area of Science:

  • Pediatric Critical Care Medicine
  • Quality Improvement Science
  • Cardiovascular Research

Background:

  • Fever post-cardiac arrest is associated with worse neurological outcomes in pediatric patients.
  • Effective fever management is crucial for improving survival and recovery after cardiac arrest.
  • Current targeted temperature management (TTM) protocols require optimization for pediatric populations.

Purpose of the Study:

  • To implement a comprehensive TTM bundle in a pediatric intensive care unit (PICU).
  • To reduce the percentage of time patients experienced fever (temperature > 38°C) after cardiac arrest.
  • To achieve a target reduction in febrile time from 7% to 3.5%.

Main Methods:

  • A prospective quality improvement initiative was conducted over 16 months (April 2021 to June 2022).
  • A TTM bundle including standardized temperature goals, cooling blanket protocols, scheduled antipyretics, and shivering management was implemented.
  • Data from 29 pre-intervention historical control patients were compared with 46 intervention period patients.

Main Results:

  • The median percentage of febrile time per patient decreased from 7% (IQR, 0-13%) to 0% (IQR, 0-3%) (p < 0.001).
  • Fewer patients experienced fever at any time during the intervention period (16/46 vs. 21/29; 37% reduction; p = 0.002).
  • No significant association was found between the intervention and the development of hypothermia (< 35°C).

Conclusions:

  • Implementation of a TTM bundle effectively reduces fever duration and frequency in pediatric cardiac arrest survivors.
  • This quality improvement project demonstrates the successful application of a TTM bundle in a PICU setting.
  • The TTM bundle is a valuable strategy for improving post-cardiac arrest care in pediatric patients.
Abstract