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Updated: Jun 6, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
Association between post-stroke depression and post-stroke sleep disorders: a systematic review and meta-analysis
Xingling Zhang1, Linyu Huang1, Jie Zhang1
1School of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Post-stroke depression (PSD) and post-stroke sleep disorders (PSSD) frequently occur together after a stroke. Research indicates a significant positive correlation between these conditions, suggesting interventions for one may benefit the other.
Area of Science:
- Neurology
- Psychiatry
- Public Health
Background:
- Post-stroke depression (PSD) and post-stroke sleep disorders (PSSD) are prevalent concurrent conditions in stroke survivors.
- Early identification of PSD and PSSD is crucial for optimizing stroke recovery and patient prognosis.
Purpose of the Study:
- To systematically investigate and quantify the association between post-stroke depression and post-stroke sleep disorders.
Main Methods:
- A comprehensive literature search was conducted across multiple databases (PubMed, Embase, Web of Science, etc.) up to May 2024.
- Data from 16 studies involving 2,284 patients were analyzed using RevMan and Stata software.
- Independent screening and quality assessment were performed by two researchers.
Main Results:
- The meta-analysis revealed a significant positive correlation between PSD and PSSD (pooled r-value = 0.52).
- The pooled Fisher's Z statistic was 0.58 (95% CI = 0.52-0.65, P < 0.00001).
Conclusions:
- Evidence confirms a positive correlation between post-stroke depression and post-stroke sleep disorders.
- Targeting PSSD may help reduce the incidence of PSD, and improving PSD could enhance sleep quality in stroke patients.
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