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Published on: November 15, 2024
Laser interstitial thermal therapy for treatment of a recurrent skull base chordoma: illustrative case
William D Chow1, Vance T Lehman1, Jamie J Van Gompel1
1Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota.
Background:
The authors applied laser interstitial thermal therapy (LITT) to a recurrent skull base chordoma, which has not been previously described.
Observations:
A 63-year-old man was initially diagnosed with an 8-cm destructive clival chordoma, which was aggressively resected endoscopically but recurred despite multiple operations, proton radiation therapy, and chemotherapy. The patient underwent uncomplicated LITT for a subtemporal mass, which palliated the tumor for 10 months. However, it did not ultimately prevent the need for resection, although it may have delayed the surgery.
Lessons:
This case study demonstrates the feasibility and safety of LITT in treating these typically surgically challenging tumors. https://thejns.org/doi/10.3171/CASE24534.

