Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

1
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1
Bacterial Flora of the Large Intestine01:29

Bacterial Flora of the Large Intestine

385
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
385
What is Monogastric Digestion?01:50

What is Monogastric Digestion?

70.6K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
70.6K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

317
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
317

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum to "World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update - IV - A quality appraisal with the AGREE II instrument" [World Allergy Organ J 15(2) (February 2022) 100613].

The World Allergy Organization journal·2026
Same author

Iron in breastfed infants and behavior at 3 years: a randomized trial.

Scientific reports·2026
Same author

Probiotic Human Study Design and Reporting (PRODARE): Recommendations to Improve Research Practice.

Advances in nutrition (Bethesda, Md.)·2026
Same author

Growth and safety of infants with cow's milk allergy receiving a new hydrolyzed rice protein-based formula containing 2-fucosyllactose and lacto-N-neotetraose: protocol for a randomized clinical trial. The RIGHT-GO study.

Frontiers in nutrition·2026
Same author

Hypoallergenicity of a hydrolyzed rice protein-based formula containing 2-fucosyllactose and lacto-N-neotetraose in children with cow's milk allergy: protocol for a randomized controlled study. The RIGHT-HY study.

Frontiers in nutrition·2026
Same author

When probiotics guidelines differ: a practical guide for clinicians and researchers.

Gut microbes·2026
Same journal

Chairpersons, Speakers and Contributors.

Nestle Nutrition Institute workshop series·2024
Same journal

The Art of Chewing: Optimizing Early Life Sensory Exposure to Develop Healthy Eating Behavior.

Nestle Nutrition Institute workshop series·2024
Same journal

What Does Healthy Microbiome Development Look Like? State of the Art and Beyond.

Nestle Nutrition Institute workshop series·2024
Same journal

Strategies to Develop Balanced Dietary Habits: Solving the Dilemma.

Nestle Nutrition Institute workshop series·2024
Same journal

Understanding the Ovarian Clock - Essential Knowledge for Pediatricians.

Nestle Nutrition Institute workshop series·2024
Same journal

Foreword.

Nestle Nutrition Institute workshop series·2024
See all related articles

Related Experiment Video

Updated: Jun 6, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

9.5K

Integrating Next-Generation Evidence-Based Medicine Into Clinical Studies on Gut Microbiota Modulation.

Hania Szajewska1

  • 1Department of Paediatrics, Medical University of Warsaw, Warsaw, Poland.

Nestle Nutrition Institute Workshop Series
|November 25, 2024
PubMed
Summary
This summary is machine-generated.

Applying Evidence-Based Medicine (EBM) to gut microbiota research presents challenges and opportunities. New EBM approaches can improve patient-centered gut health studies if data quality, privacy, and patient involvement are prioritized.

More Related Videos

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

2.8K
Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota
06:23

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Published on: February 15, 2019

14.1K

Related Experiment Videos

Last Updated: Jun 6, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

9.5K
Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

2.8K
Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota
06:23

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Published on: February 15, 2019

14.1K

Area of Science:

  • Integrative Medicine
  • Microbiome Research
  • Health Sciences

Background:

  • Evidence-Based Medicine (EBM) integrates evidence, clinical expertise, and patient values.
  • EBM faces criticism for overemphasizing randomized controlled trials and lacking patient involvement.
  • These EBM critiques are particularly relevant to the complexities of gut microbiota research.

Purpose of the Study:

  • To explore the challenges and opportunities of applying EBM to gut microbiota research.
  • To examine the relevance of EBM criticisms to gut health studies.
  • To discuss the potential and limitations of next-generation EBM methods in this field.

Main Methods:

  • Literature review and critical analysis of EBM principles.
  • Discussion of EBM's applicability to gut microbiota research.
  • Exploration of emerging next-generation EBM methodologies.

Main Results:

  • EBM application in gut microbiota research faces unique challenges.
  • Next-generation EBM methods offer potential for improved understanding and interventions.
  • Concerns regarding data quality, privacy, and patient involvement with new EBM approaches.

Conclusions:

  • Evolving EBM must ensure new methods are robust, transparent, and patient-centric.
  • Careful implementation is crucial for advancing gut microbiota research outcomes.
  • Balancing innovation with ethical considerations is key for patient-centered care.