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Recurrent pleomorphic adenoma: Epidemiology and surgical challenges; a single tertiary center experience

  • 0Surgical Oncology department, Oncology Center Mansoura University (OCMU), Mansoura, Egypt.
Journal of Stomatology, Oral and Maxillofacial Surgery +

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November 25, 2024

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November 25, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Recurrent pleomorphic adenoma presents surgical challenges, particularly after inadequate primary surgery. Proper surgical technique and multidisciplinary care are crucial for optimal outcomes and minimizing complications like facial nerve injury.

Area Of Science

  • Head and Neck Surgery
  • Surgical Oncology
  • Pathology

Background

  • Recurrent pleomorphic adenoma remains a significant surgical challenge, especially following suboptimal initial procedures.
  • While less common, understanding its recurrence patterns is vital for effective patient management.

Purpose Of The Study

  • To analyze epidemiological, radiological, and pathological data of patients with recurrent pleomorphic adenoma and Carcinoma ex pleomorphic adenoma.
  • To evaluate risk factors, surgical treatments, and outcomes for these challenging conditions.

Main Methods

  • Retrospective analysis of patients treated between February 2007 and April 2024.
  • Inclusion of cases with recurrent pleomorphic adenoma and Carcinoma ex pleomorphic adenoma.
  • Comprehensive data collection on patient demographics, tumor characteristics, surgical interventions, and outcomes.

Main Results

  • 35 patients with recurrent pleomorphic adenoma were analyzed; parotid and submandibular glands were most affected.
  • Inadequate primary surgery, including simple enucleation (48.6%), was linked to shorter recurrence intervals and increased facial nerve injury (71.4%).
  • Three cases of Carcinoma ex pleomorphic adenoma (1.4%) were associated with young age and long-standing recurrence.

Conclusions

  • Surgery is the primary treatment for pleomorphic adenoma; inadequate initial surgery increases risks.
  • Facial nerve injury is associated with factors like simple enucleation and tumor fragmentation.
  • Multidisciplinary approaches, including radiation, and surgery by trained specialists are recommended; Carcinoma ex pleomorphic adenoma requires specialized management due to its poor prognosis.

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