Related Experiment Video
Updated: Jun 6, 2025

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Modifiable and non-modifiable risk factors affecting surgical failure after revision ACL reconstruction: a cohort
Hyun-Soo Moon1,2, Min Jung1,2, Chong-Hyuk Choi1,2
1Arthroscopy and Joint Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Multiple revision surgeries, higher osteoarthritis grade, and shallower femoral tunnels increase the risk of revision anterior cruciate ligament (ACL) reconstruction failure. Understanding these factors is key for better patient outcomes and counseling.
Area of Science:
- Orthopedic Surgery
- Sports Medicine
- Biomechanical Engineering
Background:
- Limited research exists on factors influencing revision anterior cruciate ligament (ACL) reconstruction outcomes.
- Understanding revision ACL reconstruction failure is crucial for improving clinical results and patient counseling.
- This study analyzes factors contributing to surgical failure in revision ACL reconstruction.
Purpose of the Study:
- To identify demographic, perioperative, intraoperative, and postoperative factors associated with surgical failure in revision ACL reconstruction.
- To provide insights for optimizing surgical techniques and patient selection for revision ACL reconstruction.
- To enhance preoperative counseling by clarifying risk factors for revision ACL reconstruction failure.
Main Methods:
- Retrospective review of 58 patients undergoing single-bundle revision ACL reconstruction (2010-2020) with ≥2-year follow-up.
- Patients classified into non-failure (NF) and failure (F) groups based on graft re-tear, laxity, or rotational instability.
- Comparative and multivariate regression analyses performed on patient data to determine failure predictors.
Main Results:
- The failure group (F) had a higher incidence of multiple revision surgeries (P=0.001), increased preoperative osteoarthritis grade (P=0.001), and shallower femoral tunnel depth (P=0.002).
- Surgical failure was independently associated with multiple revision surgeries, preoperative osteoarthritis, and femoral tunnel depth.
- The failure group exhibited poorer subjective and objective clinical outcomes at final follow-up.
Conclusions:
- Surgical failure in revision ACL reconstruction is influenced by both non-modifiable (multiple revisions, osteoarthritis) and modifiable (femoral tunnel depth) factors.
- Identifying these factors can guide surgeons in managing complex cases and improving revision ACL reconstruction success rates.
- Femoral tunnel depth represents a critical modifiable factor that surgeons can optimize during revision ACL reconstruction procedures.
More Related Videos
05:30Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion
Published on: February 14, 2025
05:07Author Spotlight: Implementing the Enhanced Recovery After Surgery Concept in Rehabilitation Following Anterior Cruciate Ligament Reconstruction
Published on: March 1, 2024