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Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: May 12, 2026

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects

Published on: August 14, 2013

Direct selective laser trabeculoplasty: A retrospective study.

Giovanni Fossati^1,2, Marco Trevisi², Usman Sarodia¹

¹Ophthalmology Department, University Hospitals of Leicester NHS Trust, Leicester, UK.

European Journal of Ophthalmology

|November 26, 2024

Summary

This summary is machine-generated.

Direct Selective Laser Trabeculoplasty (DSLT) effectively lowered intraocular pressure (IOP) in glaucoma patients, showing comparable safety to traditional SLT. This procedure offers a promising alternative for managing ocular hypertension and open-angle glaucoma.

Keywords:

GLAUCOMA Laser surgery < GLAUCOMA aqueous humor dynamics < GLAUCOMA biochemistry/physiology of aqueous < GLAUCOMA glaucoma medical therapies < GLAUCOMA

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Last Updated: May 12, 2026

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Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction

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Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Area of Science:

Ophthalmology
Glaucoma Research
Laser Therapy

Background:

Open-angle glaucoma (OAG) and ocular hypertension (OHT) are leading causes of irreversible blindness.
Selective Laser Trabeculoplasty (SLT) is a common treatment, but alternatives are sought.
Direct Selective Laser Trabeculoplasty (DSLT) is an emerging laser treatment for glaucoma.

Purpose of the Study:

To evaluate the effectiveness and safety of Direct Selective Laser Trabeculoplasty (DSLT).
To compare DSLT outcomes with existing literature on SLT and previous DSLT studies.

Main Methods:

A retrospective study included 15 eyes from 10 patients with OAG or OHT.
DSLT was performed in June 2023 at University Hospitals of Leicester, UK.
Success was defined by a ≥20% IOP reduction or decreased medication use while maintaining target IOP.

Main Results:

DSLT achieved success in 73.3% of eyes (11 out of 15) by the fourth month.
Mean IOP decreased from 22.7±4.4 mmHg to 18.7±4.2 mmHg (p=0.008).
No significant adverse events requiring intervention were observed, and best-corrected visual acuity (BCVA) remained stable.

Conclusions:

DSLT demonstrates comparable effectiveness and safety profiles to traditional SLT.
DSLT represents a viable alternative treatment option for patients with OAG and OHT.
Further research into DSLT may solidify its role in glaucoma management.