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A rare complication of infantile hemangioma: Kasabach-Merritt phenomenon
Ricardo A Caravantes1, José Manuel Toralla2, Daniela Saenz1
1Department of Medical Research, Universidad Francisco Marroquín, 6ta calle final zona 10, Guatemala 01010, Guatemala.
Abstract:
Infantile hemangiomas are the most common type of vascular tumors, affecting ~5% of infants within the first weeks of life. In rare instances, these tumors can lead to Kasabach-Merritt phenomenon (KMP), a life-threatening consumptive coagulopathy characterized by thrombocytopenia, microangiopathic hemolytic anemia, and hypofibrinogenemia. In the present case, a 20-month-old patient is diagnosed with KMP. This case report highlights the challenges in diagnosis and management, reinforcing the importance of multidisciplinary approach.
Insights
Infantile hemangiomas, common vascular tumors in infants, can rarely cause Kasabach-Merritt phenomenon (KMP), a severe bleeding disorder. This case underscores the complexity of KMP diagnosis and management in pediatric patients.
Area of Science:
- Pediatric Oncology
- Hematology
- Vascular Biology
Background:
- Infantile hemangiomas are the most frequent vascular tumors in infants, occurring in approximately 5% of newborns.
- Kasabach-Merritt phenomenon (KMP) is a rare but life-threatening complication of infantile hemangiomas.
- KMP is a consumptive coagulopathy involving thrombocytopenia, microangiopathic hemolytic anemia, and hypofibrinogenemia.
