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Major sight-threatening eye disorders and mental disorders.
Xing-Xuan Dong1, Hui-Hui Hu1, Zhi-Qi Ying1
1School of Public Health; The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Suzhou, China.
Acta Ophthalmologica
|November 26, 2024
Summary
Major sight-threatening eye disorders frequently co-occur with mental health conditions like depression and anxiety. Income disparities may influence the prevalence of these comorbidities, highlighting the need for integrated care.
Area of Science:
- Ophthalmology
- Psychiatry
- Public Health
Background:
- Major sight-threatening eye disorders and mental disorders represent significant global health burdens.
- Understanding the interplay between these conditions is crucial for comprehensive patient care and public health strategies.
Purpose of the Study:
- To systematically review and synthesize the existing literature on comorbidities between major sight-threatening eye disorders and mental disorders.
- To investigate the prevalence, associations, and potential influencing factors of these comorbidities.
Main Methods:
- A systematic review and meta-analysis of studies published up to December 2023 from major databases (PubMed, Embase, Web of Science, Cochrane Library).
- Inclusion of 67 studies, excluding those with only laboratory results or non-representative sampling.
- Meta-analyses were conducted using a random-effects model.
Main Results:
- Diabetic retinopathy (DR) and depression (30% prevalence) and DR and anxiety (29% prevalence) were the most common comorbidities.
- Significant associations were found between glaucoma and depression/anxiety/schizophrenia, age-related macular degeneration (AMD) and depression, and DR and depression.
- Lower income was identified as a factor associated with increased comorbidity between glaucoma and depression.
Conclusions:
- Major sight-threatening eye disorders are significantly associated with mental disorders, particularly depression and anxiety.
- The burden of these comorbidities is substantial and may be exacerbated by socioeconomic factors like income disparities.
- Healthcare providers should proactively screen for and manage comorbidities to improve patient outcomes.
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