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Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice
Published on: February 11, 2019
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Intestinal graft-versus-host disease.
Luis Carlos Anflor1, Luana Posser2, Julia Silva Sarkis3
1Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Brasil.
Revista Espanola De Enfermedades Digestivas
|November 26, 2024
Summary
Graft-versus-host disease (GVHD) is a serious complication after stem cell transplants, causing inflammation and gut damage. This case report highlights the crucial role of imaging in diagnosing and managing GVHD.
Area of Science:
- Medicine
- Immunology
- Radiology
Background:
- Graft-versus-host disease (GVHD) is a major complication following allogeneic hematopoietic cell transplantation.
- It involves an immune response where donor immune cells attack host tissues, leading to inflammation and organ damage, particularly in the gastrointestinal tract.
- GVHD significantly contributes to morbidity and mortality in transplant recipients.
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