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Updated: Jun 6, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Seasonal Patterns in Eosinophilic Esophagitis-Related Emergency Department Visits: A National Database Analysis
Chun-Wei Pan1, Alejandro Nieto Dominguez1, Daniel Guifarro1
1Department of Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, USA.
Introduction:
This study investigates seasonal variations in eosinophilic esophagitis (EoE)-related emergency department visits among adults.
Methods:
We analyzed the National Emergency Department Sample (2016-2021), identifying adult patients with EoE using ICD-10 codes. Generalized additive models assessed seasonal patterns.
Results:
Among 18,791 EoE-related emergency department visits, a significant seasonal variation was observed, peaking in summer and nadiring in winter. This pattern was consistent across all US regions.
Conclusion:
Seasonal dietary habits and social behaviors likely contribute to EoE exacerbations. Healthcare providers should emphasize management strategies during high-risk periods, particularly summer months and weekends.
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