Related Experiment Video
Updated: Jun 6, 2025
05:41
Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
534
Occupational Physical Activity and Regular Exercise Are Inversely Correlated with Thyroid Function in Patients with
Marko Vuletić1, Dean Kaličanin2, Ana Barić Žižić1
1Department of Nuclear Medicine, University Hospital of Split, Spinčićeva 1, 21000 Split, Croatia.
Diseases (Basel, Switzerland)
|November 26, 2024
Summary
Occupational physical activity (OPA) is linked to poorer thyroid function and higher autoimmunity in Hashimoto's thyroiditis patients, while recreational exercise (RE) shows beneficial effects on thyroid health.
Area of Science:
- Endocrinology
- Immunology
- Occupational Health
Background:
- Hashimoto's thyroiditis (HT) is an autoimmune disease affecting thyroid function.
- The impact of different types of physical activity on HT is not fully understood.
Purpose of the Study:
- To investigate the correlations between occupational physical activity (OPA) and recreational exercise (RE) with thyroid function and autoimmunity in HT patients.
Main Methods:
- A study included 438 individuals diagnosed with HT.
- Data on OPA and RE were collected via self-report questionnaires.
- Correlations were assessed between thyroid function markers (TSH, T3, T4, fT4, TgAb, TPOAb, vitamin D) and physical activity levels.
Main Results:
- Increased OPA correlated with decreased fT4, increased TSH, and increased TPOAb antibodies.
- Increased RE correlated with decreased TSH, decreased TgAb antibodies, and increased vitamin D levels.
Conclusions:
- Occupational physical activity is associated with reduced thyroid function and elevated thyroid autoimmunity in HT.
- Recreational exercise demonstrates a positive association with improved thyroid health markers in HT patients.
Related Concept Videos
01:20Synthesis and Regulation of Thyroid Hormones
4.2K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.2K
01:18Functions of Thyroid Hormones
2.5K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.5K
01:17Hormones and Bone Tissue
2.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.6K
01:23The Thyroid Gland
3.6K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
3.6K
01:20Exercise and Cardiovascular Response
737
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
737
01:17Exercise and Cardiac Output
923
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
923