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Animal experimental study of 3D-printed titanium implants based on magnesium-zinc ion surface modification to promote
Shuo Huang1, Fang Guo1, Ning Liu1
1College of Stomatology, Xi'an Medical University, The Third Affiliated Hospital of Xi'an Medical University, Research Center for Tooth and Maxillofacial Tissue Regeneration and Restoration, Xi'an, Shaanxi, 710021, China.
Objective:
The study aimed to investigate whether 3D-printed titanium implants modified with magnesium and zinc ion surfaces can promote oral soft-tissue closure.
Method:
New Zealand Great White rabbits were selected as experimental animals, and the left and right side mandibular teeth of each animal were randomly divided into an experimental group and control group, each with 18 cases, and the bilateral first premolar teeth were extracted after general anesthesia, and implants were implanted into the magnesium/zinc ionized surface-treated and the surface-untreated groups, respectively.
Results:
Under naked-eye observation, the combination of implant material and surrounding soft tissue in the experimental group was significantly better than that in the control group; fluorescence staining showed that the fluorescence density value of the experimental group was significantly higher than that of the control group (p < 0.05).
Conclusions:
3D-printed titanium implants based on magnesium-zinc ion surface modification promote oral soft-tissue closure with significant results.
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