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Correlation between carotid and/or subclavian atherosclerotic plaque and coronary atherosclerotic disease

Jing Li1,2,3,4, Lingyun Jia1,2,3, Jing Li5

  • 1Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Road, Beijing, 100053, China.

BMC Cardiovascular Disorders
|November 26, 2024
PubMed

Insights

Detecting both carotid and subclavian atherosclerotic plaque (CAP & SAP) significantly increases the risk of coronary atherosclerosis disease (CASD). Combined evaluation of CAP & SAP offers better prediction of CASD than CAP alone.

Area of Science:

  • Vascular Medicine
  • Cardiology
  • Diagnostic Imaging

Background:

  • Coronary atherosclerosis disease (CASD) is a major cause of ischemic heart disease.
  • Carotid atherosclerotic plaque (CAP) and subclavian atherosclerotic plaque (SAP) are indicators of systemic atherosclerosis.

Purpose of the Study:

  • To investigate the correlation between the presence of CAP and/or SAP and the severity of CASD.
  • To evaluate the predictive value of combined CAP and SAP detection for CASD.

Main Methods:

  • 1,242 patients with suspected coronary artery disease were assessed for CAP and SAP using color Doppler flow imaging (CDFI).
  • Patients were categorized into four groups: non-CAP & non-SAP, only-SAP, only-CAP, and CAP & SAP.
  • Correlation between plaque presence and coronary angiography findings was analyzed.

Main Results:

  • The incidence of CASD and main coronary artery disease was higher in the CAP & SAP group compared to the CAP-only group.
  • The CAP & SAP group showed a significantly higher detection rate of three-vessel disease (3-VD).
  • Presence of CAP & SAP, along with multiple cardiovascular risk factors, was associated with an approximately 81.7% incidence of coronary artery main artery disease.

Conclusions:

  • Combined evaluation of CAP and SAP using CDFI provides higher predictive value for CASD than CAP alone.
  • Early detection and intervention for coronary atherosclerotic stenosis are crucial for reducing ischemic heart disease events.
Abstract

Keywords:
Carotid arteryColor doppler flow imagingCoronary arteryCoronary atherosclerotic diseaseSubclavian artery

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