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Editorial for Special Issue "Brain Tumor Microenvironment"

Gianluca Trevisi1,2, Annunziato Mangiola1

  • 1Department of Neurosciences, Imaging and Clinical Sciences, G. D'Annunzio University Chieti-Pescara, 66100 Chieti, Italy.

Cancers
|November 27, 2024
PubMed
Summary

The tumor microenvironment (TME) impacts cancer progression and treatment outcomes. Understanding the TME is crucial for developing effective cancer therapies.

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...