Related Experiment Video

Updated: Jun 6, 2025

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
09:36

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Published on: July 28, 2022

2.2K

Efficacy and Safety of Orogastric vs. Nasogastric Tube Feeding in Preterm Infants: A Systematic Review and

Huazi Liu1, Qiang Fei1, Tianming Yuan1

  • 1Department of Neonatology, Children's Hospital, School of Medicine, Zhejiang University, National Clinical Research Center for Child Health and Disease, Hangzhou 310052, China.

Children (Basel, Switzerland)
|November 27, 2024
PubMed

Insights

Nasogastric tube feeding in preterm infants is faster for establishing enteral nutrition compared to orogastric tube feeding. Further research is needed to assess adverse outcomes associated with different feeding routes.

Area of Science:

  • Neonatal care
  • Pediatric nutrition
  • Gastroenterology

Background:

  • Enteral nutrition delivery in preterm infants utilizes nasogastric (NG) or orogastric (OG) tubes.
  • Both NG and OG routes present distinct advantages and disadvantages.
  • Comparative analysis of these feeding methods is crucial for optimizing infant care.

Purpose of the Study:

  • To compare the efficacy of NG versus OG tube feeding in preterm infants.
  • To evaluate the impact of feeding route on infant growth and development.
  • To assess the incidence of adverse outcomes associated with NG and OG tube feeding.

Main Methods:

  • Meta-analysis of randomized controlled trials (RCTs).
  • Searched major databases: PubMed, Embase, Web of Science, Cochrane Central.
  • Assessed risk of bias using Cochrane tool v2; data analysis with Review Manager 5.4.

Main Results:

  • Included 6 studies with 265 preterm infants.
  • Orogastric tube feeding significantly delayed time to full enteral feeding (MD = 1.62, p < 0.01).
  • No significant difference in time to regain birth weight; insufficient data on adverse events.

Conclusions:

  • Nasogastric tube feeding facilitates quicker establishment of full enteral feeding in preterm infants compared to orogastric.
  • Further investigation is necessary to fully understand the impact of feeding routes on adverse events.
Abstract

Keywords:
adverse eventsgrowthmeta-analysisoral/nasal routepreterm infants

More Related Videos

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition00:04

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

10.6K
Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling07:11

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling

Published on: February 5, 2019

8.9K

Related Concept Videos

Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
201
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
81
Endotracheal Intubation I: Procedure01:15

Endotracheal Intubation I: Procedure

Endotracheal or ET intubation is a critical medical procedure used to secure a patient's airway, often in acute respiratory distress, apnea, upper airway obstruction, ineffective clearance of secretions, high risk for aspiration, or during general anesthesia.
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
752
Endotracheal Tube Extubation01:24

Endotracheal Tube Extubation

Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
409