Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reoperation for failed antireflux operations.

A G Little, M K Ferguson, D B Skinner

    The Journal of Thoracic and Cardiovascular Surgery
    |April 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Naphthenic acid fraction compounds reduce the reproductive success of wood frogs (Rana sylvatica) by affecting offspring viability.

    Environmental pollution (Barking, Essex : 1987)·2022
    Same author

    Inguinal Hernia Operated on under Local Anaesthesia.

    Atlanta journal-record of medicine·2022
    Same author

    Corrigendum to: Sex-specific differences in swimming, aerobic metabolism and recovery from exercise in adult coho salmon (<i>Oncorhynchus kisutch</i>) across ecologically relevant temperatures.

    Conservation physiology·2022
    Same author

    Sex-specific differences in swimming, aerobic metabolism and recovery from exercise in adult coho salmon (<i>Oncorhynchus kisutch</i>) across ecologically relevant temperatures.

    Conservation physiology·2021
    Same author

    Thyroid hormone regulation of thermal acclimation in ectotherms: Physiological mechanisms and ecoevolutionary implications.

    Molecular and cellular endocrinology·2021
    Same author

    Clinical predictors of donor antibody titre and correlation with recipient antibody response in a COVID-19 convalescent plasma clinical trial.

    Journal of internal medicine·2020
    Same journal

    Bridging Pediatric and Young Adult Cancer Survivorship: Defining the Thoracic Surgeon's Role Across the Continuum.

    The Journal of thoracic and cardiovascular surgery·2026
    Same journal

    Beyond compensatory expansion: Extending 3-dimensional computed tomography volumetry toward lung-preserving local therapy.

    The Journal of thoracic and cardiovascular surgery·2026
    Same journal

    A CALL FOR STANDARDIZATION OF HYBRID ARCH FROZEN ELEPHANT TRUNK OUTCOMES REPORTING.

    The Journal of thoracic and cardiovascular surgery·2026
    Same journal

    Pediatric Mitral Valve Surgery: Current Practice from the European Congenital Heart Surgeons Association Congenital Database Analysis.

    The Journal of thoracic and cardiovascular surgery·2026
    Same journal

    Rethinking Failure to Rescue in Cardiac Surgery.

    The Journal of thoracic and cardiovascular surgery·2026
    Same journal

    Undersized Fontan conduits are not without risk.

    The Journal of thoracic and cardiovascular surgery·2026
    See all related articles

    Repeat antireflux surgery outcomes worsen with each subsequent operation due to impaired esophageal function. Definitive reoperations using healthy tissue are recommended, with a transthoracic approach preferred for multiple prior procedures.

    Area of Science:

    • Gastroenterology
    • Surgical Oncology
    • Digestive System Surgery

    Background:

    • Gastroesophageal reflux disease (GERD) management is well-studied in primary cases.
    • Outcomes of repeat antireflux surgery after failed primary operations are less understood.
    • This study investigates outcomes in patients undergoing multiple revisional antireflux procedures.

    Purpose of the Study:

    • To evaluate the impact of prior antireflux operations on the success of repeat procedures.
    • To correlate patient outcomes with the number of previous surgeries.
    • To identify factors influencing the success of revisional antireflux surgery.

    Main Methods:

    • Retrospective analysis of 61 patients undergoing repeat antireflux surgery.
    • Patients categorized into three groups based on the number of prior operations (1, 2, or 3+).

    Related Experiment Videos

  • Assessment included clinical outcomes, manometry, pH testing, endoscopy, and operative complications.

    • Main Results:

    • Clinical success rates decreased significantly with an increasing number of prior operations (85% for 1, 66% for 2, 42% for 3+).
    • Esophageal function, incidence of esophagitis, and surgical complications worsened progressively with more prior surgeries.
    • Operative mortality was 4.9%, with complications increasing from 27% to 75% in groups A to C.

    Conclusions:

    • Recurrent GERD after one prior operation is similar to primary GERD.
    • Outcomes of repeat antireflux surgery significantly deteriorate with multiple prior procedures due to impaired esophageal function and tissue damage.
    • Definitive reoperations, potentially involving resection and reconstruction with healthy tissue, are crucial. A transthoracic approach is recommended for first reoperations and mandatory after multiple procedures.