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Design, Testing, and Validation of a Soft Robotic Sensor Array Integrated with Flexible Electronics for Mapping

Abdellatif Ait Lahcen1, Michael Labib1, Alexandre Caprio1

  • 1Dalio Institute of Cardiovascular Imaging, Department of Radiology, Weill Cornell Medicine, New York, NY 10021, USA.

Micromachines
|November 27, 2024
PubMed
Summary

This study introduces a novel 64-electrode soft robotic catheter for cardiac mapping. The device offers improved electrode coverage and conformability, enhancing electrogram acquisition for arrhythmia diagnosis and treatment.

Keywords:
cardiac mappingcatheterflexible printed circuit board (PCB)minimally invasive proceduresoft robotic sensor arrays

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Research
  • Robotics in Medicine

Background:

  • Current cardiac mapping techniques have limitations in electrode coverage, anatomical conformity, and cost.
  • Accurate electrophysiological data is essential for diagnosing and treating cardiac arrhythmias.

Purpose of the Study:

  • To design, test, and validate a 64-electrode soft robotic catheter for enhanced cardiac mapping.
  • To address the limitations of existing cardiac mapping technologies with a conformable, high-density electrode system.

Main Methods:

  • Development of a dual-layer flexible printed circuit board (PCB) integrated into a soft robotic sensor array (SRSA).
  • In vitro testing of the SRSA for mechanical integrity, electrode contact, and environmental resilience.
  • In vivo validation using a porcine model to assess deployment, conformability, and electrogram acquisition.

Main Results:

  • The soft robotic sensor array (SRSA) demonstrated successful deployment and anatomical conformity in a porcine model.
  • High-density electrode array enabled rapid 2-second data acquisition with detailed spatial and temporal resolution.
  • Clear and consistent cardiac signals were recorded across all electrodes, validating the system's performance.

Conclusions:

  • The catheter-deployable SRSA represents a significant advancement in integrating soft robotics and stretchable electronics for clinical cardiac mapping.
  • This technology offers improved performance for detailed cardiac mapping to guide ablation therapy and other interventions.
  • Future work will focus on further refining anatomically conformable devices for clinical applications.