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Updated: Jul 1, 2026

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
Published on: August 28, 2015
Poly-Amino-β-Cyclodextrin Microparticles for the Reduction of Xenobiotics and Emerging Contaminants, Including
Wojciech Ciesielski1, Damian Kulawik1, Beata Girek1
1Faculty of Science and Technology, Jan Dlugosz University in Czestochowa, Armii Krajowej Ave. 13/15, 42-201 Czestochowa, Poland.
Abstract:
The contamination of the natural environment by xenobiotics and emerging contaminants, including pharmaceuticals, poses significant risks to ecosystems and human health. Among these contaminants, hormones and pharmaceutical compounds are particularly concerning due to their persistence and potential biological effects even at low concentrations. In this study, we investigated the efficacy of poly-amino-β-cyclodextrin (PA-β-CD) microparticles in adsorbing and reducing specific xenobiotics and pharmaceuticals from aqueous solutions. Our research focused on four contaminants: two hormones, testosterone and progesterone, and two pharmaceutical drugs, diclofenac and carbamazepine. High-performance liquid chromatography (HPLC) was employed to quantify the adsorption capacity and efficiency of PA-β-CD microparticles.
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