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Study of Bacillus cereus as an Effective Multi-Type A Trichothecene Inactivator
Fernando Abiram García-García1,2, Eliseo Cristiani-Urbina2, Liliana Morales-Barrera2
1Laboratorio Nacional en Salud, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Tlalnepantla 54090, Mexico.
Microorganisms
|November 27, 2024
Summary
This study identified Bacillus cereus bacteria capable of inactivating multiple type A trichothecene mycotoxins. This discovery offers a novel biological solution for mycotoxin contamination in cereal grains.
Area of Science:
- Food Science
- Microbiology
- Mycotoxicology
Background:
- Type A trichothecenes are prevalent mycotoxins in stored grains, often occurring as co-contaminants.
- Existing methods for mycotoxin control face challenges with multiple contaminants.
Purpose of the Study:
- To isolate and characterize facultative anaerobic bacteria with the ability to inactivate multiple type A trichothecenes.
- To evaluate the mycotoxin inactivation and biosorption capacity of selected bacterial strains.
Main Methods:
- Isolation of facultative anaerobic bacteria from broiler proventriculus.
- In vitro production of type A trichothecenes (neosolaniol, HT-2 toxin, T-2 toxin).
- Mycotoxin inactivation assays and biosorption studies using bacterial isolates and a consortium.
Main Results:
- A bacterial consortium demonstrated significant degradation of neosolaniol (64.55%), HT-2 toxin (22.96%), and T-2 toxin (20.84%).
- Bacillus cereus isolate showed effective removal of T-2 toxin (28.35%), HT-2 toxin (32.84%), and neosolaniol (27.14%).
- Biosorption was a primary mechanism, particularly for T-2 toxin (86.10%) and neosolaniol (68.64%) by B. cereus.
Conclusions:
- Bacillus cereus exhibits significant potential as a biological agent for inactivating and binding multiple type A trichothecenes.
- This research presents the first evidence of B. cereus effectively managing diverse type A trichothecene mycotoxins.
