Related Experiment Video

Updated: Jun 25, 2026

Mouse Abdominal Aortic Aneurysm Model Induced by Perivascular Application of Elastase
04:49

Mouse Abdominal Aortic Aneurysm Model Induced by Perivascular Application of Elastase

Published on: February 11, 2022

5.2K

The Effect of Arterial Elongation on Isolated Common Iliac Artery Pathologies

Ádám Szőnyi1, Balázs Bence Nyárády1, Márton Philippovich1

  • 1Heart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary.

Life (Basel, Switzerland)
|November 27, 2024
PubMed

Insights

Iliac artery occlusions occur in straighter vessels, while aneurysms develop in more elongated systems. Vessel geometry significantly impacts common iliac artery (CIA) pathologies.

Area of Science:

  • Vascular Surgery
  • Radiology
  • Biomedical Engineering

Background:

  • Common iliac artery (CIA) pathologies, including stenosis, occlusion, and aneurysms, significantly impact patient health.
  • Understanding the relationship between vessel geometry and CIA pathologies is crucial for diagnosis and treatment.

Purpose of the Study:

  • To investigate the influence of vessel geometry on steno-occlusive and dilatative common iliac artery (CIA) pathologies.
  • To differentiate geometric characteristics between CIA stenosis, occlusion, and aneurysm groups.

Main Methods:

  • Retrospective analysis of 100 participants, including 60 with unilateral CIA pathology (stenosis, occlusion, aneurysm) and 40 controls.
  • 3D reconstruction of the aortoiliac region from computed tomography angiography.
  • Quantification of vessel elongation (tortuosity index, absolute average curvature) and bifurcation parameters.

Main Results:

  • Occlusion group showed higher tortuosity index (TI) and absolute average curvature (AAC) on the contralateral side.
  • Aneurysm group exhibited higher AAC on the ipsilateral side and significantly higher TI and AAC in iliac arteries compared to other groups.
  • Age influenced most elongation parameters; AAC was associated with obesity.

Conclusions:

  • Common iliac artery occlusions are associated with relatively straight iliac arteries.
  • Unilateral, isolated CIA aneurysms are more likely to occur in elongated aortoiliac systems.
  • Vessel geometry plays a distinct role in the development of different CIA pathologies.
Abstract

Keywords:
aneurysmaortacurvatureelongationiliac arteriesocclusionstenosistortuosity

More Related Videos

Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta07:12

Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta

Published on: September 8, 2023

2.2K
Development of a Murine Model for Femoral Artery Anastomotic Stenosis05:41

Development of a Murine Model for Femoral Artery Anastomotic Stenosis

Published on: April 18, 2025

99

Related Concept Videos

Abdominal Aorta01:25

Abdominal Aorta

Once the aorta traverses the diaphragmatic plane at the aortic hiatus, it is known as the abdominal aorta. This anatomical structure is positioned leftward of the spinal column, encased within a cocoon of adipose tissue behind the peritoneal cavity. It terminates at the L4 vertebra, where it splits into the common iliac arteries. Prior to this bifurcation, the abdominal aorta gives rise to several vital branches.
The celiac trunk, a singular artery, divides into the left gastric artery, which...
Arteries of Lower Limbs01:20

Arteries of Lower Limbs

The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular artery,...
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...