Triple Spectral Line Imaging of Whole-Body Human Skin: Equipment, Image Processing, and Clinical Data

Multispectral imaging can provide objective quantitative data on various clinical pathologies, e.g., abnormal content of bio-substances in human skin. Performance of diagnostics increases with decreased spectral bandwidths of imaging; from this point, ultra-narrowband laser spectral line imaging is well suited for diagnostic applications. In this study, 40 volunteers participated in clinical validation tests of a newly developed prototype device for triple laser line whole-body skin imaging. The device comprised a vertically movable high-resolution camera coupled with a specific illumination unit-a side-emitting optical fiber spiral that emits simultaneously three RGB laser spectral lines at the wavelengths 450 nm, 520 nm, and 628 nm. The prototype's design details, skin spectral image processing, and the obtained first clinical data are reported and discussed.