Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

317
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
317
Metabolic States of the Body: Fasting and Starvation01:24

Metabolic States of the Body: Fasting and Starvation

1.1K
During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Distinct compositional changes but shared quantitative microbiome and anti-inflammatory modulations by diet.

Cell reports·2026
Same author

The gut microbiota predicts and time-restricted feeding delays experimental colitis.

Gut microbes·2025
Same author

Serotonin reuptake transporter deficiency promotes liver steatosis and impairs intestinal barrier function in obese mice fed a Western-style diet.

Neurogastroenterology and motility·2023
Same author

Resveratrol Attenuates Mast Cell Mediated Allergic Reactions: Potential for Use as a Nutraceutical in Allergic Diseases?

Molecular nutrition & food research·2022

Related Experiment Video

Updated: Jun 6, 2025

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
08:06

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice

Published on: November 27, 2019

8.9K

Effect of Intermittent Fasting on Immune Parameters and Intestinal Inflammation.

Eva Haasis1, Anna Bettenburg1, Axel Lorentz1

  • 1Institute of Nutritional Medicine, University of Hohenheim, 70599 Stuttgart, Germany.

Nutrients
|November 27, 2024
PubMed
Summary

Intermittent fasting (IF), including alternate day fasting (ADF) and time-restricted eating (TRE), shows anti-inflammatory effects in animal models and healthy humans. These fasting methods may improve gut health by reducing inflammation and altering microbiota composition.

Keywords:
alternate day fastingcolitisimmune parametersinflammationintermittent fastingtime-restricted feeding

More Related Videos

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

9.5K
Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes
08:14

Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes

Published on: May 8, 2016

27.4K

Related Experiment Videos

Last Updated: Jun 6, 2025

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
08:06

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice

Published on: November 27, 2019

8.9K
An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

9.5K
Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes
08:14

Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes

Published on: May 8, 2016

27.4K

Area of Science:

  • Gastroenterology
  • Nutrition Science
  • Immunology

Background:

  • Intermittent fasting (IF) encompasses various eating patterns like alternate day fasting (ADF) and time-restricted eating (TRE).
  • IF has been linked to disease prevention and management, including inflammatory bowel disease (IBD).
  • Limited research exists on IF specifically in IBD patients, necessitating inclusion of studies on healthy individuals.

Purpose of the Study:

  • To review existing animal and human studies on the impact of IF on intestinal inflammation.
  • To evaluate the anti-inflammatory effects and impact on microbiota composition of different IF methods.

Main Methods:

  • Systematic review of 20 animal and human studies.
  • Analysis of studies on ADF and TRE in animal models of colitis.
  • Inclusion of human studies on IF (including Ramadan fasting, TRE, and ADF) in healthy individuals due to scarcity of IBD patient data.

Main Results:

  • Animal studies: ADF and TRE improved histological scores, reduced inflammatory markers and oxidative stress, and modulated microbiota composition.
  • Human studies (excluding Ramadan fasting): TRE and ADF demonstrated anti-inflammatory effects, significantly reducing C-reactive protein (CRP) levels and other inflammatory markers.
  • TRE also positively impacted microbiota composition and the circadian oscillation of clock genes in healthy individuals.

Conclusions:

  • ADF and TRE exhibit anti-inflammatory properties and may benefit gut health.
  • The efficacy of TRE and ADF in healthy individuals appears linked to the duration of uninterrupted fasting periods.
  • While animal studies showed benefits regardless of fasting duration, further research is needed, especially in IBD patients.