Hotspots and future trends of dermatofibrosarcoma protuberans

Area of Science:

• Oncology
• Dermatology
• Bibliometrics

Background:

• Dermatofibrosarcoma protuberans (DFSP) is a soft tissue sarcoma with significant patient impact due to its infiltrative growth and high recurrence.
• Challenges in DFSP management include extensive surgical requirements and associated patient dysfunction, aesthetic concerns, and economic burdens.

Purpose of the Study:

• To analyze the global publication landscape of Dermatofibrosarcoma protuberans (DFSP) over 32 years.
• To identify research hotspots and emerging trends in DFSP through bibliometric analysis.
• To provide insights for future research directions and clinical decision-making in DFSP.

Main Methods:

• Bibliometric analysis of 1588 DFSP-related publications from 1990-2022.
• Utilized Web of Science Core Collection (WoSCC) database.
• Included analysis of collaborative networks, journal co-citations, reference co-citations, and keyword clustering.

Main Results:

• The United States and China are the leading countries in DFSP research output.
• A highly cited paper focused on Imatinib Mesylate treatment for advanced DFSP.
• Key research areas include diagnosis, COL1A1-PDGFB fusion gene, drug and surgical treatments, fibrosarcomatous transformation, and immunotherapy.

Conclusions:

• DFSP research faces ongoing clinical challenges.
• This bibliometric study offers valuable insights into the evolution and future trajectory of DFSP research.