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Sjogren's Syndrome Presenting as Hypokalemic Paralysis Secondary to Distal Renal Tubular Acidosis: A Case Report
Ashwath Ravisankar1, Varshini Thiruvadi2, Souwdamini Sethuram3
1Internal Medicine, OSF Saint Francis Medical Center, Peoria, USA.
Abstract:
Sjogren's syndrome (SS) is an autoimmune disease affecting multiple exocrine glands such as salivary and lacrimal glands, with focal lymphocytic infiltration. The disease predominantly affects women. The classic presentation is xerostomia and keratoconjunctivitis. In adult populations, tubulointerstitial nephritis, which can manifest as renal tubular acidosis (RTA), is the most prevalent renal manifestation of SS. However, in pediatric populations, RTA only occurs in 7.1-19.2% of cases with renal potassium wasting or hypokalemic paralysis. Here, we describe a case of SS manifesting with hypokalemic paralysis with underlying distal renal tubular acidosis (dRTA).
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