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Updated: Jun 6, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
The Effectiveness of Cardiac Rehabilitation Programs in Improving Cardiovascular Outcomes: Systematic Review and
Arhum Mahmood1, Rubela Ray2, Shaikh Shams T Bin Salam3
1Internal Medicine, Henry Ford Health System, Detroit, USA.
Insights
Cardiac rehabilitation (CR) programs significantly reduce cardiovascular disease (CVD) mortality and improve patient function. Implementing these vital secondary prevention programs globally remains a challenge, requiring wider adoption and standardized protocols.
Area of Science:
- Cardiology
- Public Health
- Rehabilitation Medicine
Background:
- Cardiovascular diseases (CVDs) are leading causes of global mortality and disability.
- Secondary prevention interventions are crucial for managing CVDs and improving patient outcomes.
- Cardiac rehabilitation (CR) is recognized as a key component of CVD treatment.
Purpose of the Study:
- To systematically review and meta-analyze the impact of CR on mortality, morbidity, functional capacity, and quality of life in CVD patients.
- To assess the effectiveness of CR as a secondary prevention strategy for cardiovascular events.
Main Methods:
- Systematic review and meta-analysis of 12 studies, including randomized controlled trials and cohort studies.
- Analysis of data on all-cause mortality, International Classification of Functioning, Disability and Health (ICF) domains, and other relevant patient outcomes.
Main Results:
- CR programs were found to be effective in reducing all-cause mortality (RR=0.74).
- Significant favorable effects of CR were observed in the ICF domains of body functions (SMD=0.55).
- CR improves functional status and lowers mortality rates in patients with cardiovascular diseases.
Conclusions:
- CR programs are a significant and effective component of secondary CVD prevention.
- There is a need for improved global implementation and standardization of CR programs to increase patient access and adherence.
- Addressing suboptimal CR program implementation is essential for maximizing patient benefits.
Abstract:
Cardiovascular diseases (CVDs) are some of the most common conditions and the major contributors to death and disability globally, hence the need for proper secondary prevention interventions. Cardiac rehabilitation (CR) programs have been recognized as an essential component in the treatment of CVDs with the goal of decreasing the risk of new cardiovascular events and improving the quality of life. This systematic review and meta-analysis sought to determine the impact of CR as a form of CVD treatment on mortality, morbidity, functional capacity, and quality of life amongst the patient population. The search resulted in 12 studies that fulfilled the inclusion criteria, which included both randomized controlled trials as well as cohort studies. The meta-analysis, therefore, showed that the CR program is effective in reducing all-cause mortality (RR=0 74, 95% CI: 0.62-0. Favorable effects of intervention regarding participation measures were found in the International Classification of Functioning, Disability and Health (ICF) domains of body functions (pool standardized mean differences (SMD)= 0.55, 95% CI: 0.43-0.68). The results confirm the significance of CR programs as an essential element of secondary prevention of CVDs, stressing the ability of CR to lower mortality rates and improve patients' functional status. Despite this, the implementation of CR programs continues to be suboptimal globally for various healthcare facilities; hence the requirement for interventions to ensure that more patients incorporate the protocols and adapt uniform CR protocols.
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