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Incidental Ovarian Uptake in Bone Scintigraphy.

Amin Saber Tanha1, Sareh Hosseini2, Ehsan Soltani3

  • 1From the Nuclear Medicine Research Center.

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An unexpected finding on a bone scan led to the diagnosis of an adult-type granulosa cell tumor in a woman with breast cancer. Hybrid imaging, combining bone scintigraphy and CT, proved valuable for diagnosis.

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Area of Science:

  • Oncology
  • Nuclear Medicine
  • Radiology

Background:

  • Incidental findings during cancer staging require careful evaluation.
  • Ovarian uptake on bone scintigraphy is uncommon and can represent various pathologies.

Purpose of the Study:

  • To report a rare case of incidental ovarian uptake on bone scintigraphy.
  • To highlight the diagnostic utility of hybrid imaging in identifying ovarian tumors.

Main Methods:

  • A whole-body bone scan was performed for breast cancer staging.
  • Hybrid imaging (bone scintigraphy with CT) was utilized for further evaluation.
  • Surgical resection and histopathological examination were performed for definitive diagnosis.

Main Results:

  • An unexpected focal 99mTc-MDP uptake was identified in the right ovary.
  • Final pathology confirmed an adult-type granulosa cell tumor.
  • No other tumor sources were found during staging surgery.

Conclusions:

  • Hybrid imaging enhances diagnostic accuracy for incidental findings on bone scintigraphy.
  • Adult-type granulosa cell tumors can present as incidental ovarian uptake.
  • Multidisciplinary tumor board decisions are crucial for managing unexpected findings.