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Effect of Exercise-Based Cardiac Rehabilitation on Patients With Chronic Heart Failure After Transcatheter Aortic

Jingjin Song1, Xiang Chen, Bin Wang

  • 1Author Affiliation: Department of Cardiology, Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China (Song, Chen, Wang, Cheng, and Wang).

Journal of Cardiopulmonary Rehabilitation and Prevention
|November 27, 2024
PubMed

Insights

Personalized exercise-based cardiac rehabilitation (CR) significantly improved cardiopulmonary function and exercise tolerance in patients with chronic heart failure (HF) after transcatheter aortic valve replacement (TAVR). Quality of life also improved in the exercise training group.

Area of Science:

  • Cardiology
  • Cardiovascular Rehabilitation
  • Exercise Physiology

Background:

  • Chronic heart failure (HF) poses significant challenges, particularly post-transcatheter aortic valve replacement (TAVR).
  • Optimizing recovery and functional capacity after TAVR in HF patients is crucial for long-term outcomes.
  • Individualized exercise interventions may enhance rehabilitation effectiveness.

Purpose of the Study:

  • To evaluate the impact of exercise-based cardiac rehabilitation (CR) with individualized exercise prescription.
  • To assess its effects on patients with chronic heart failure (HF) following transcatheter aortic valve replacement (TAVR).
  • To compare outcomes between an exercise training (ET) group and a control group in a randomized controlled trial.

Main Methods:

  • Sixty patients with chronic HF post-TAVR were randomized into control (conventional rehabilitation) and ET (personalized CR based on cardiopulmonary exercise test - CPX) groups.
  • Interventions lasted 12 weeks, with assessments including CPX parameters, echocardiography, 6-minute walk test (6MWT), and quality of life (Minnesota Life with Heart Failure Questionnaire).
  • Symptom-restricted CPX was performed to guide exercise prescription and assess safety.

Main Results:

  • The ET group demonstrated significant improvements in anaerobic threshold, peak oxygen uptake, peak oxygen pulse, peak power, and left ventricular ejection fraction compared to the control group (P < .05).
  • Significant increases in 6-minute walk test distance were observed in the ET group versus the control group (P < .05).
  • The ET group reported significantly lower scores on the Minnesota Life with Heart Failure Questionnaire, indicating improved quality of life (P < .05).

Conclusions:

  • Exercise-based CR with individualized exercise prescription is effective in improving cardiopulmonary function in chronic HF patients post-TAVR.
  • This approach enhances exercise tolerance and significantly boosts the quality of life for these patients.
  • Personalized CR represents a valuable therapeutic strategy for HF patients undergoing TAVR.
Abstract

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