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Pyridoxine (Vitamin B6) effectively treated infantile spasms and hypsarrhythmia in three infants within six days. This study presents case histories and discusses the positive outcomes of this vitamin therapy.
Area of Science:
- Pediatrics
- Neurology
- Clinical Pharmacology
Background:
- Infantile spasms are a severe epilepsy syndrome in infants.
- Hypsarrhythmia is a characteristic EEG pattern associated with infantile spasms.
- Pyridoxine (Vitamin B6) is essential for neurological function.
Abstract:
A total dose of 0.2-0.4 g.kg-1 pyridoxine stopped infantile spasms with hypsarrhythmia in three infants within five to six days. The case histories are presented and the results briefly discussed.