Updated cancer burden in oldest old: A population-based study using 2022 Globocan estimates

Area of Science:

• Geriatric Oncology
• Global Health
• Epidemiology

Background:

• The global population aged 80 years or older is projected to triple by 2050.
• This demographic shift will significantly increase the overall cancer burden.
• Understanding cancer incidence and mortality in this age group is crucial for public health planning.

Purpose of the Study:

• To estimate cancer incidence and mortality in individuals aged 80+ for 2022.
• To project cancer incidence and mortality for this population in 2050.
• To analyze these trends globally, by region, and by income level.

Main Methods:

• Utilized GLOBOCAN 2022 estimates for cancer cases and deaths in those aged 80+.
• Calculated age-standardized incidence rates (ASIR) and mortality rates (ASMR).
• Projected 2050 figures assuming constant incidence and mortality rates.

Main Results:

• In 2022, an estimated 2.6 million new cancer cases and 2.1 million deaths occurred in the 80+ population.
• Lung, colorectal, and prostate cancers were the most common.
• By 2050, 7.4 million new cases and 6 million deaths are projected, with over 200% increases in China, India, and Africa.

Conclusions:

• The increasing cancer burden in the oldest old presents a major challenge for healthcare systems.
• Resource-tailored adaptations are necessary to manage this growing health issue.
• The oldest old must be included in cancer control policies and research efforts.