Jove
Visualize
Contact Us

Related Concept Videos

Overview of Metabolism01:40

Overview of Metabolism

29.5K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
29.5K
Microbial Nutrition01:28

Microbial Nutrition

1
Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
1
Lipid Catabolism01:25

Lipid Catabolism

1
Triglycerides serve as crucial long-term energy storage molecules in microorganisms, providing a dense source of metabolic energy. Their breakdown is mediated by lipases, which hydrolyze triglycerides into glycerol and free fatty acids. Each of these components follows distinct metabolic pathways, ultimately contributing to ATP synthesis and cellular energy homeostasis.Glycerol MetabolismGlycerol, released from triglyceride hydrolysis, is phosphorylated by glycerol kinase to form...
1
Introduction to Metabolism01:30

Introduction to Metabolism

1
Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
1
What is Metabolism?00:52

What is Metabolism?

113.3K
Overview
113.3K
Biosynthesis in Bacteria01:24

Biosynthesis in Bacteria

1
Biosynthesis in bacteria is a fundamental anabolic process that generates essential macromolecules, including proteins, nucleic acids, lipids, and polysaccharides. These macromolecules are critical for cellular growth, replication, and function. The process is tightly regulated and energetically linked to catabolic pathways to ensure optimal resource utilization.Biosynthetic pathways begin with precursor metabolites such as pyruvate, acetyl-CoA, and glucose-6-phosphate derived from glycolysis,...
1

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Opposing range-dependent interactions create complex spatial patterns of antibiotic tolerance in multispecies biofilms.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Metabolic feedbacks drive population dynamics and can lead to oscillations among leaf bacteria.

Nature communications·2026
Same author

LysG-driven transcriptional network rewiring underlies lineage-specific phenotypes in Mycobacterium tuberculosis.

Nature communications·2026
Same author

Antagonism as a foraging strategy in microbial communities.

Science (New York, N.Y.)·2025
Same author

Disentangling the feedback loops driving spatial patterning in microbial communities.

NPJ biofilms and microbiomes·2025
Same author

Polysaccharide breakdown products drive degradation-dispersal cycles of foraging bacteria through changes in metabolism and motility.

eLife·2024
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 6, 2025

Investigation of Microbial Cooperation via Imaging Mass Spectrometry Analysis of Bacterial Colonies Grown on Agar and in Tissue During Infection
09:49

Investigation of Microbial Cooperation via Imaging Mass Spectrometry Analysis of Bacterial Colonies Grown on Agar and in Tissue During Infection

Published on: November 18, 2022

2.0K

A framework for understanding collective microbiome metabolism.

Matthias Huelsmann1,2,3, Olga T Schubert4,5, Martin Ackermann4,5,6

  • 1Department of Environmental Systems Science, Swiss Federal Institute of Technology Zurich (ETH Zurich), Zurich, Switzerland. matthias.huelsmann@alumni.ethz.ch.

Nature Microbiology
|November 28, 2024
PubMed
Summary
This summary is machine-generated.

Microbiome members perform partial metabolism due to natural selection for proteome efficiency. This individual optimization drives collective metabolism and ecosystem functions through shared metabolic intermediates.

More Related Videos

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
00:06

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Published on: August 23, 2019

6.9K
Bioreactor Assembly for Continuous Culture of Complex Fecal Communities
09:37

Bioreactor Assembly for Continuous Culture of Complex Fecal Communities

Published on: April 25, 2025

218

Related Experiment Videos

Last Updated: Jun 6, 2025

Investigation of Microbial Cooperation via Imaging Mass Spectrometry Analysis of Bacterial Colonies Grown on Agar and in Tissue During Infection
09:49

Investigation of Microbial Cooperation via Imaging Mass Spectrometry Analysis of Bacterial Colonies Grown on Agar and in Tissue During Infection

Published on: November 18, 2022

2.0K
Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
00:06

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Published on: August 23, 2019

6.9K
Bioreactor Assembly for Continuous Culture of Complex Fecal Communities
09:37

Bioreactor Assembly for Continuous Culture of Complex Fecal Communities

Published on: April 25, 2025

218

Area of Science:

  • Microbial ecology
  • Metabolic biochemistry
  • Evolutionary biology

Background:

  • Microbiome metabolism is crucial for ecosystem functions.
  • Individual microbes often exhibit partial metabolic capabilities.
  • A mechanistic framework explaining this partial metabolism and functional distribution is lacking.

Purpose of the Study:

  • To propose a framework explaining partial metabolism in microbiome members.
  • To elucidate how metabolic functions are distributed within microbiomes.
  • To link individual proteome efficiency to collective microbiome metabolism.

Main Methods:

  • Theoretical framework development.
  • Analysis of metabolic fluxes and protein investment.
  • Case study using the carbon cycle.

Main Results:

  • Natural selection for proteome efficiency drives partial metabolism in individual microbes.
  • Partial metabolism enables efficient collective metabolism within microbiomes.
  • Specific metabolic motifs and interactions arise under conditions favoring proteome efficiency.

Conclusions:

  • Proteome efficiency is a key driver of partial metabolism in microbiomes.
  • This individual-level selection leads to emergent collective metabolic functions.
  • The proposed framework explains functional distribution and metabolic interactions in microbial communities.