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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Sudden infant death syndrome in infants evaluated by apnea programs in California
Insights
Home apnea monitoring for infants at risk of SIDS has unproven benefits. A study found SIDS rates were similar whether or not home monitoring was recommended, with some deaths linked to monitoring issues.
Area of Science:
- Pediatrics
- Neonatal Care
- Public Health
Background:
- Home apnea/bradycardia monitoring is common for infants at risk of Sudden Infant Death Syndrome (SIDS).
- The proven efficacy and benefits of home monitoring for these infants remain uncertain.
- Previous evaluations by infant apnea programs have not definitively established monitoring's impact.
Purpose of the Study:
- To investigate the Sudden Infant Death Syndrome (SIDS) rate among infants evaluated by infant apnea programs.
- To identify risk factors associated with SIDS and other causes of death in monitored infants.
- To assess the effectiveness and outcomes of home apnea monitoring recommendations.
Main Methods:
- A survey was conducted among 31 infant apnea programs and 10 home monitor vendors in California.
- Data were collected on 26 infant deaths, including causes and circumstances.
- Statistical analysis compared risk factors and monitoring recommendations for 3,406 infants over 5 years.
Main Results:
- Of 26 infant deaths, 13 (50%) were attributed to SIDS.
- Abnormal sleep studies did not predict mortality.
- Fifteen infants died despite a recommendation for home monitoring; seven deaths involved monitoring errors or noncompliance.
- Four deaths were due to nonaccidental trauma.
Conclusions:
- Home apnea monitoring for infants at risk of SIDS has not demonstrated proven benefits.
- Monitoring recommendations were more frequent for term infants, SIDS siblings, and those seen at referral centers.
- Infants recommended for monitoring faced the same SIDS risk as those not monitored.
Abstract:
Home apnea/bradycardia monitoring is frequently used in the management of infants at increased risk for sudden infant death syndrome (SIDS). However, some infants have died despite evaluation by infant apnea programs, and the benefits of home monitoring remain unproven. To determine the SIDS rate and risk factors of infants evaluated by infant apnea programs, 31 apnea programs and ten home monitor vendors in California were surveyed. Eleven (35%) of the apnea programs and four (40%) of the vendors responded. Information was obtained on 26 infants who died. Thirteen (50%) deaths were due to SIDS. Abnormal sleep studies did not predict death. Fifteen infants died despite a recommendation for home monitoring. Seven deaths occurred in association with technical errors or noncompliance with monitoring. Four deaths were due to nonaccidental trauma. The apnea programs evaluated 3,406 infants during a 5-year period; 1,841 had monitoring recommended. Term infants with apnea, subsequent siblings of SIDS victims, and infants evaluated at referral centers were more likely to have monitoring recommended than premature infants with apnea or infants evaluated at nonreferral centers (P less than .0001). Infants who had monitoring recommended were at equal risk of dying of SIDS as those who did not.
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