Related Experiment Video

Updated: Jun 6, 2025

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies
09:08

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies

Published on: June 2, 2021

1.8K

CRISPR in 3D: Innovations in Disease Modelling and Personalized Medicine

Louis J Gautier

    Biotechniques
    |November 28, 2024
    PubMed
    Summary

    The CRISPR-Cas gene editing tool, since 2013, revolutionizes biological research. Its combination with advanced 3D culture and commercial tech enables better disease modeling and personalized medicine.

    Keywords:
    3D-CultureBiotechnologyCRISPRDisease ModellingGene EditingGenetic EngineeringOrgan-on-a-ChipPersonalized MedicineRegenerative Medicinegenomic

    More Related Videos

    Designing, Packaging, and Delivery of High Titer CRISPR Retro and Lentiviruses via Stereotaxic Injection11:28

    Designing, Packaging, and Delivery of High Titer CRISPR Retro and Lentiviruses via Stereotaxic Injection

    Published on: May 23, 2016

    17.5K
    Genome Editing and Directed Differentiation of hPSCs for Interrogating Lineage Determinants in Human Pancreatic Development09:37

    Genome Editing and Directed Differentiation of hPSCs for Interrogating Lineage Determinants in Human Pancreatic Development

    Published on: March 5, 2017

    13.1K

    Related Concept Videos

    CRISPR01:59

    CRISPR

    Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
    49.5K
    CRISPR and crRNAs02:53

    CRISPR and crRNAs

    Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
    The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
    16.7K
    What is Genetic Engineering?00:49

    What is Genetic Engineering?

    Overview
    73.6K