Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Effects of EDTA on End-Point Detection Methods01:18

Effects of EDTA on End-Point Detection Methods

Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a result, EDTA...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The critical role of accurate neoplastic cell percentage (NCP) assessment: investigating targeted training strategies for pulmonary biopsy and cytology specimens.

Virchows Archiv : an international journal of pathology·2026
Same author

SpermFACS: Validation of a Highly Sensitive Sperm Cell Sorting Method for Sexual Assault Casework Analysis.

Analytical chemistry·2026
Same author

Genetic variant interpretation in tumours in the French national ring trials Gen&Tiss - main criteria of improvement.

Virchows Archiv : an international journal of pathology·2026
Same author

Expression of antibody-drug conjugate targets in post-mortem samples of breast cancer metastases and normal tissue.

Nature communications·2025
Same author

ctDNA detectability and representativeness in seven body liquids from patients with metastatic breast cancer.

Nature communications·2025
Same author

Postmortem microbiological sampling: a prospective ESGFOR-supported study on relevance, timing, and site selection.

Virchows Archiv : an international journal of pathology·2025

Related Experiment Video

Updated: Jun 12, 2026

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG
08:46

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG

Published on: March 7, 2017

16.9K

Enhancing postmortem diagnostics: over a decade of ISO 17020 accreditation and guidelines implementation in forensic

Wouter Van Den Bogaert1,2, Joke Wuestenbergs3, Bram Bekaert4,3

  • 1Forensic Biomedical Sciences, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium. wouter.vandenbogaert@uzleuven.be.

Forensic Science, Medicine, and Pathology
|November 28, 2024
PubMed
Summary

Implementing ISO 17020 accreditation enhanced postmortem diagnostics (PMD) quality assurance in forensic pathology. This study details developing specific standard operating procedures (SOPs) to reduce diagnostic errors and improve accuracy.

Keywords:
AccreditationForensic autopsyGuidelinesMinimum standardsQuality assurance

More Related Videos

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

11.4K
DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens
10:38

DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens

Published on: February 1, 2020

7.4K

Related Experiment Videos

Last Updated: Jun 12, 2026

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG
08:46

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG

Published on: March 7, 2017

16.9K
Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

11.4K
DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens
10:38

DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens

Published on: February 1, 2020

7.4K

Area of Science:

  • Forensic Pathology
  • Medical Diagnostics
  • Quality Assurance

Background:

  • Forensic autopsies are vital for determining cause and manner of death.
  • Postmortem diagnostics (PMD) present challenges, including potential diagnostic errors.
  • A lack of tailored quality assurance (QA) programs hinders forensic pathology.

Purpose of the Study:

  • To explore enhancements in PMD following ISO 17020 accreditation.
  • To detail the development and implementation of SOPs for forensic practice.
  • To provide strategies for qualitative standardization in PMD.

Main Methods:

  • Adoption of ISO 17020 accreditation at a Belgian forensic institute.
  • Development and implementation of label-specific standard operating procedures (SOPs).
  • Comparative review of international guidelines for adapting directives into local protocols.

Main Results:

  • Over a decade of experience in enhancing PMD processes.
  • Successful implementation of SOPs tailored to various death types.
  • Demonstrated improvement in the efficacy and standardization of PMD.

Conclusions:

  • ISO 17020 accreditation significantly improves PMD quality.
  • Standardized SOPs are essential for minimizing errors in forensic pathology.
  • Adapting international guidelines into local protocols enhances PMD effectiveness worldwide.